Potent neutralization of hepatitis A virus reveals a receptor mimic mechanism and the receptor recognition site.

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作者： Xiangxi,Wang ^[1] ; Ling,Zhu ^[2] ; Minghao,Dang ^[3] ; Zhongyu,Hu ^[4] ; Qiang,Gao ^[3] ; Shuai,Yuan ^[5] ; Yao,Sun ^[3] ; Bo,Zhang ^[3] ; Jingshan,Ren ^[5] ; Abhay,Kotecha ^[2] ; Thomas S,Walter ^[2] ; Junzhi,Wang ^[2] ; Elizabeth E,Fry ^[4] ; David I,Stuart ^[6] ; Zihe,Rao ^[6]

作者单位： National Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of Science, Beijing 100101, China; xiangxi@ibp.ac.cn liz@strubi.ox.ac.uk dave@strubi.ox.ac.uk raozh@xtal.tsinghua.edu.cn. ^[1] Division of Structural Biology, University of Oxford, Oxford OX3 7BN, United Kingdom. ^[2] National Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of Science, Beijing 100101, China. ^[3] National Institutes for Food and Drug Control, Beijing 100050, China. ^[4] Sinovac Biotech Co., Ltd., Beijing 100085, China. ^[5] Division of Structural Biology, University of Oxford, Oxford OX3 7BN, United Kingdom; xiangxi@ibp.ac.cn liz@strubi.ox.ac.uk dave@strubi.ox.ac.uk raozh@xtal.tsinghua.edu.cn. ^[6] Diamond Light Sources, Didcot OX11 0DE, United Kingdom. ^[7] Laboratory of Structural Biology, School of Medicine, Tsinghua University, Beijing 100084, China. ^[8]

关键词 entry neutralizing mechanism picornavirus receptor recognition uncoating