IGF-IR cooperates with ERα to inhibit breast cancer cell aggressiveness by regulating the expression and localisation of ECM molecules.
第一作者:
Nikolaos A,Afratis
第一单位:
Biochemistry, Biochemical Analysis &Matrix Pathobiology Res. Group, Laboratory of Biochemistry, Department of Chemistry, University of Patras, Patras 26110, Greece.;Biotech Research and Innovation Center, University of Copenhagen, Ole Maaløes Vej 5, 2200 Copenhagen N, Denmark.
作者:
医学主题词
乳腺肿瘤(Breast Neoplasms);细胞运动(Cell Movement);细胞增殖(Cell Proliferation);雌激素受体α(Estrogen Receptor alpha);细胞外基质(Extracellular Matrix);人类(Humans);受体, IGF1型(Receptor, IGF Type 1);信号传导(Signal Transduction)
DOI
10.1038/srep40138
PMID
28079144
发布时间
2018-11-13
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