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Optimizing the Use of Linaclotide in Patients with Constipation-Predominant Irritable Bowel Syndrome: An Expert Consensus Report.

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第一作者： Enrique,Rey

第一单位： Division of Digestive Diseases, Hospital Universitario Clínico de San Carlos, Madrid, Spain. enrique.rey@salud.madrid.org.;Department of Medicine, Instituto de Investigacion San Carlos (IdISSC), School of Medicine, Complutense University, Madrid, Spain. enrique.rey@salud.madrid.org.

作者： Enrique,Rey ^[1] ; Fermín,Mearin ^[2] ; Javier,Alcedo ^[3] ; Constanza,Ciriza ^[4] ; Silvia,Delgado-Aros ^[5] ; Teresa,Freitas ^[6] ; Miguel,Mascarenhas ^[7] ; Miguel,Mínguez ^[8] ; Javier,Santos ^[9] ; Jordi,Serra ^[10]

作者单位： Division of Digestive Diseases, Hospital Universitario Clínico de San Carlos, Madrid, Spain. enrique.rey@salud.madrid.org.;Department of Medicine, Instituto de Investigacion San Carlos (IdISSC), School of Medicine, Complutense University, Madrid, Spain. enrique.rey@salud.madrid.org. ^[1] Institute of Functional and Motor Digestive Disorders, Centro Médico Teknon, Barcelona, Spain. ^[2] Division of Digestive Diseases, Hospital Universitario Miguel Servet, Zaragoza, Spain. ^[3] Division of Digestive Diseases, Hospital Universitario Doce de Octubre, Madrid, Spain. ^[4] Neuro-Enteric Translational Science (NETS) Research Group, Barcelona, Spain. ^[5] Institut Hospital del Mar d'Investigacions Mèdiques (IMIM), Centro Hospitalar Vila Nova de Gaia, Porto, Portugal. ^[6] CUF Porto Hospital, Porto, Portugal. ^[7] Division of Digestive Diseases, Hospital Clínic, Universitat of Valencia, Valencia, Spain. ^[8] Digestive System Research Unit, Laboratory of Neuro-Immuno-Gastroenterology, Valld'Hebron Institut de Recerca VHIR, Barcelona, Spain.;Department of Gastroenterology, Hospital Universitari Vall d'Hebron, Barcelona, Spain.;Department of Medicine, Universitat Autònoma de Barcelona, Barcelona, Spain. ^[9] Department of Medicine, Universitat Autònoma de Barcelona, Barcelona, Spain.;Motility and Functional Gut Disorders Unit, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), University Hospital Germans Trias i Pujol, Barcelona, Spain. ^[10]

关键词 Abdominal pain Bloating Constipation Constipation-predominant irritable bowel syndrome Gastroenterology Linaclotide Patient management Recommendations

医学主题词便秘(Constipation);胃肠病用药(Gastrointestinal Agents);人类(Humans);肠易激综合征(Irritable Bowel Syndrome);肽类(Peptides);受体, 心钠素(Receptors, Atrial Natriuretic Factor);治疗结果(Treatment Outcome)

DOI 10.1007/s12325-016-0473-8

PMID 28083815

发布时间 2026-01-05

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