Radiochemical studies, pre-clinical investigation and preliminary clinical evaluation of <sup>170</sup>Tm-EDTMP prepared using in-house freeze-dried EDTMP kit.

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作者： Tapas,Das ^[1] ; Ajit,Shinto ^[2] ; Koramadai K,Kamaleshwaran ^[2] ; Haladhar D,Sarma ^[3] ; Sahiralam Khan,Mohammed ^[4] ; Arpit,Mitra ^[5] ; Sangita,Lad ^[5] ; M G R,Rajan ^[6] ; Sharmila,Banerjee ^[7]

作者单位： Radiopharmaceuticals Chemistry Section, Radiochemistry and Isotope Group, Bhabha Atomic Research Centre, Trombay, Mumbai 400085, India; Homi Bhabha National Institute, Anushaktinagar, Mumbai 400094, India. Electronic address: tdas@barc.gov.in. ^[1] Department of Nuclear Medicine & PET, Kovai Medical Centre and Hospital, Coimbatore, Tamil Nadu 641014, India. ^[2] Radiation Biology and Health Sciences Division, Bhabha Atomic Research Centre, Trombay, Mumbai 400085, India. ^[3] Isotope Production and Applications Division, Bhabha Atomic Research Centre, Trombay, Mumbai 400085, India. ^[4] Radiation Medicine Cnetre, Bhabha Atomic Research Centre, Mumbai 400012, India. ^[5] Homi Bhabha National Institute, Anushaktinagar, Mumbai 400094, India; Radiation Medicine Cnetre, Bhabha Atomic Research Centre, Mumbai 400012, India. ^[6] Radiopharmaceuticals Chemistry Section, Radiochemistry and Isotope Group, Bhabha Atomic Research Centre, Trombay, Mumbai 400085, India; Homi Bhabha National Institute, Anushaktinagar, Mumbai 400094, India. ^[7]

关键词 (170)Tm (170)Tm-EDTMP Freeze-dried EDTMP kit Metastatic bone pain palliation Pharmacokinetics