Clinically Relevant Levels of 4-Aminopyridine Strengthen Physiological Responses in Intact Motor Circuits in Rats, Especially After Pyramidal Tract Injury.

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第一作者： Anil,Sindhurakar

第一单位： 1 Burke Medical Research Institute, White Plains, NY, USA.

作者： Anil,Sindhurakar ^[1] ; Asht M,Mishra ^[1] ; Disha,Gupta ^[1] ; Jennifer F,Iaci ^[2] ; Tom J,Parry ^[2] ; Jason B,Carmel ^[3]

作者单位： 1 Burke Medical Research Institute, White Plains, NY, USA. ^[1] 2 Weill Cornell Medicine, New York, NY, USA. ^[2] 3 Acorda Therapeutics, Ardsley, NY, USA. ^[3]

关键词 4-AP corticospinal electrophysiology forelimb motor cortex motor recovery pharmacology pyramidotomy rat spinal cord

主题词 4-氨基吡啶(4-Aminopyridine);动物(Animals);中枢神经系统药物(Central Nervous System Agents);药物评价, 临床前(Drug Evaluation, Preclinical);电刺激(Electric Stimulation);肌电描记术(Electromyography);诱发电位, 运动(Evoked Potentials, Motor);女(雌)性(Female);前肢(Forelimb);微电极(Microelectrodes);运动皮质(Motor Cortex);肌, 骨骼(Muscle, Skeletal);锥体束(Pyramidal Tracts);随机分配(Random Allocation);大鼠, Sprague-Dawley(Rats, Sprague-Dawley);脊髓损伤(Spinal Cord Injuries)

DOI 10.1177/1545968316688800

PMID 28107804

发布时间 2022-03-10

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Neurorehabilitation and neural repair

2017年31卷4期

387-396页

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Clinically Relevant Levels of 4-Aminopyridine Strengthen Physiological Responses in Intact Motor Circuits in Rats, Especially After Pyramidal Tract Injury.

Neurorehabilitation and neural repair

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Neurorehabilitation and neural repair

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Clinically Relevant Levels of 4-Aminopyridine Strengthen Physiological Responses in Intact Motor Circuits in Rats, Especially After Pyramidal Tract Injury.

Neurorehabilitation and neural repair

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Neurorehabilitation and neural repair

相关期刊

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