Tryptase-catalyzed core histone truncation: A novel epigenetic regulatory mechanism in mast cells.

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第一作者： Fabio R,Melo

第一单位： Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden. Electronic address: Fabio.Melo@imbim.uu.se.

作者： Fabio R,Melo ^[1] ; Ola,Wallerman ^[2] ; Aida,Paivandy ^[2] ; Gabriela,Calounova ^[3] ; Ann-Marie,Gustafson ^[2] ; Benjamin R,Sabari ^[4] ; Giuliano,Zabucchi ^[5] ; C David,Allis ^[4] ; Gunnar,Pejler ^[6]

作者单位： Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden. Electronic address: Fabio.Melo@imbim.uu.se. ^[1] Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden. ^[2] Department of Anatomy, Physiology and Biochemistry, Swedish University of Agricultural Sciences, Uppsala, Sweden. ^[3] Laboratory of Chromatin Biology and Epigenetics, The Rockefeller University, New York, NY. ^[4] Department of Life Sciences, University of Trieste, Trieste, Italy. ^[5] Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden; Department of Anatomy, Physiology and Biochemistry, Swedish University of Agricultural Sciences, Uppsala, Sweden. Electronic address: Gunnar.Pejler@imbim.uu.se. ^[6]

关键词 H2B H2BK5ac Mast cells core histones epigenetics histone acetylation mMCP6 secretory granules serglycin serglycin proteoglycan tryptase