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Poly (glycerol sebacate) elastomer supports bone regeneration by its mechanical properties being closer to osteoid tissue rather than to mature bone.

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第一作者： S H,Zaky

第一单位： Center for Craniofacial Regeneration, Department of Oral Biology, University of Pittsburgh, USA.

作者： S H,Zaky ^[1] ; K W,Lee ^[2] ; J,Gao ^[2] ; A,Jensen ^[3] ; K,Verdelis ^[4] ; Y,Wang ^[5] ; A J,Almarza ^[6] ; C,Sfeir ^[7]

作者单位： Center for Craniofacial Regeneration, Department of Oral Biology, University of Pittsburgh, USA. ^[1] Department of Bioengineering, University of Pittsburgh, USA. ^[2] Department of Chemistry, University of Pittsburgh Dietrich School of Arts and Sciences, USA. ^[3] Center for Craniofacial Regeneration, Department of Oral Biology, University of Pittsburgh, USA; McGowan Institute for Regenerative Medicine, University of Pittsburgh, USA. ^[4] Department of Bioengineering, University of Pittsburgh, USA; McGowan Institute for Regenerative Medicine, University of Pittsburgh, USA. ^[5] Center for Craniofacial Regeneration, Department of Oral Biology, University of Pittsburgh, USA; Department of Bioengineering, University of Pittsburgh, USA; McGowan Institute for Regenerative Medicine, University of Pittsburgh, USA. ^[6] Center for Craniofacial Regeneration, Department of Oral Biology, University of Pittsburgh, USA; McGowan Institute for Regenerative Medicine, University of Pittsburgh, USA. Electronic address: csfeir@pitt.edu. ^[7]

关键词 Bone tissue engineering, poly (glycerol sebacate)Critical size defect Load-transducing scaffold Osteogenic differentiation Osteoid