Improving key enzyme activity in phenylpropanoid pathway with a designed biosensor.

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作者： Dandan,Xiong ^[1] ; Shikun,Lu ^[1] ; Jieyuan,Wu ^[1] ; Chaoning,Liang ^[2] ; Wei,Wang ^[3] ; Wenzhao,Wang ^[4] ; Jian-Ming,Jin ^[5] ; Shuang-Yan,Tang ^[6]

作者单位： CAS Key Laboratory of Microbial Physiological and Metabolic Engineering, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 100049, China. ^[1] CAS Key Laboratory of Microbial Physiological and Metabolic Engineering, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China. ^[2] School of Chemistry and Biotechnology, Yunnan Minzu University, Kunming 650500, China. ^[3] State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China. ^[4] Beijing Key Laboratory of Plant Resources Research and Development, Beijing Technology and Business University, Beijing 100048, China. Electronic address: jinjianming@btbu.edu.cn. ^[5] CAS Key Laboratory of Microbial Physiological and Metabolic Engineering, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China. Electronic address: tangsy@im.ac.cn. ^[6]

关键词 Biosensor High-throughput screening Phenylpropanoids pathway Protein engineering Resveratrol p-Coumarate:coenzyme A ligase