Multi-omics analyses reveal metabolic alterations regulated by hepatitis B virus core protein in hepatocellular carcinoma cells.

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作者： Qi,Xie ^[1] ; Fengxu,Fan ^[2] ; Wei,Wei ^[2] ; Yang,Liu ^[3] ; Zhongwei,Xu ^[2] ; Linhui,Zhai ^[4] ; Yingzi,Qi ^[2] ; Bingyu,Ye ^[2] ; Yao,Zhang ^[2] ; Sumit,Basu ^[5] ; Zhihu,Zhao ^[2] ; Junzhu,Wu ^[6] ; Ping,Xu ^[5]

作者单位： School of Basic Medical Sciences, Key Laboratory of Combinatorial Biosynthesis and Drug Discovery of Ministry of Education, School of Pharmaceutical Sciences, Wuhan University, Wuhan 430071, China. ^[1] State Key Laboratory of Proteomics, Beijing Proteome Research Centre, National Engineering Research Centre for Protein Drugs, National Centre for Protein Sciences Beijing, Institute of Radiation Medicine, Beijing 102206, China. ^[2] Anhui Medical University, Hefei 230032, China. ^[3] Departmentof Chemical &Biomolecular Engineering, National University of Singapore, 117585, Singapore. ^[4] Beijing Institute of Bioengineering, Beijing 100071, China. ^[5] Center for Pharmacometrics and Systems Pharmacology, College of Pharmacy, University of Florida, 6550 Sanger Road, Orlando, FL 32827, USA. ^[6]

主题词碱性螺旋-环-螺旋亮氨酸拉链转录因子类(Basic Helix-Loop-Helix Leucine Zipper Transcription Factors);癌, 肝细胞(Carcinoma, Hepatocellular);细胞系, 肿瘤(Cell Line, Tumor);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);糖酵解(Glycolysis);乙型肝炎病毒(Hepatitis B virus);人类(Humans);肝肿瘤(Liver Neoplasms);代谢组学(Metabolomics);蛋白质组学(Proteomics);病毒核心蛋白质类(Viral Core Proteins)

DOI 10.1038/srep41089

PMID 28112229

发布时间 2018-11-13

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Multi-omics analyses reveal metabolic alterations regulated by hepatitis B virus core protein in hepatocellular carcinoma cells.

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Multi-omics analyses reveal metabolic alterations regulated by hepatitis B virus core protein in hepatocellular carcinoma cells.

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