N-alkanol-N-cyclohexanol amine aryl esters: Multidrug resistance (MDR) reversing agents with high potency and efficacy.

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作者： Elisabetta,Teodori ^[1] ; Silvia,Dei ^[2] ; Marcella,Coronnello ^[3] ; Elisa,Floriddia ^[2] ; Gianluca,Bartolucci ^[2] ; Dina,Manetti ^[2] ; Maria Novella,Romanelli ^[2] ; Diego,Santo Domingo Porqueras ^[4] ; Milena,Salerno ^[4]

作者单位： Department of Neuroscience, Psychology, Drug Research and Child's Health, Section of Pharmaceutical and Nutraceutical Sciences, University of Florence, via Ugo Schiff 6, 50019 Sesto Fiorentino (FI), Italy. Electronic address: elisabetta.teodori@unifi.it. ^[1] Department of Neuroscience, Psychology, Drug Research and Child's Health, Section of Pharmaceutical and Nutraceutical Sciences, University of Florence, via Ugo Schiff 6, 50019 Sesto Fiorentino (FI), Italy. ^[2] Department of Health Sciences, Section of Clinical Pharmacology and Oncology, University of Florence, Viale Pieraccini 6, 50139 Firenze, Italy. ^[3] Université Paris 13, Sorbonne Paris Cité, Laboratoire CSPBAT, CNRS (UMR 7244), UFR-SMBH, 74 rue Marcel Cachin, 93017 Bobigny, France. ^[4]

关键词 Chemosensitizers Doxorubicin-resistant human erythroleukemia K562?cells (K562/DOX)MDR reversers N-alkanol-N-cyclohexanol amine aryl esters P-gp modulators Pirarubicin uptake