The p53 protein induces stable miRNAs that have the potential to modify subsequent p53 responses.

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第一作者： Miguel A,Cabrita

第一单位： Centre for Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, ON, Canada.

作者： Miguel A,Cabrita ^[1] ; Reetesh,Bose ^[1] ; Erin J,Vanzyl ^[2] ; Alyssa,Pastic ^[2] ; Kristen A,Marcellus ^[1] ; Elysia,Pan ^[1] ; Jeff D,Hamill ^[1] ; Bruce C,McKay ^[3]

作者单位： Centre for Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, ON, Canada. ^[1] Department of Biology, Carleton University, Ottawa, ON, Canada. ^[2] Centre for Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, ON, Canada; Department of Biology, Carleton University, Ottawa, ON, Canada; Institute for Biochemistry, Carleton University, Ottawa, ON, Canada. Electronic address: bruce_mckay@carleton.ca. ^[3]

关键词 BTG2 CDKN1A Mdm2 MicroRNA Microarray

主题词细胞系, 肿瘤(Cell Line, Tumor);基因表达谱(Gene Expression Profiling);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);HT29细胞(HT29 Cells);人类(Humans);微RNAs(MicroRNAs);微阵列分析(Microarray Analysis);肿瘤(Neoplasms);RNA稳定性(RNA Stability);RNA, 信使(RNA, Messenger);转录激活(Transcriptional Activation);肿瘤抑制蛋白质p53(Tumor Suppressor Protein p53)

DOI 10.1016/j.gene.2017.01.018

PMID 28119089

发布时间 2017-03-07

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The p53 protein induces stable miRNAs that have the potential to modify subsequent p53 responses.

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The p53 protein induces stable miRNAs that have the potential to modify subsequent p53 responses.

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