换一批Acrolein Is a Pathogenic Mediator of Alcoholic Liver Disease and the Scavenger Hydralazine Is Protective in Mice.
第一作者：
Wei-Yang,Chen
第一单位：
Department of Pharmacology and Toxicology, University of Louisville, Louisville, Kentucky; Alcohol Research Center, University of Louisville, Louisville, Kentucky.
作者：
关键词
ADH, alcohol dehydrogenaseALD, alcoholic liver diseaseALDH, aldehyde dehydrogenaseALT, alanine aminotransferaseAST, aspartate aminotransferaseATF, activating transcription factorApoptosisCHOPCHOP, CCAAT/enhancer-binding protein homologous proteinCYP2E1, cytochrome P4502E1ER, endoplasmic reticulumFDP-lysine, Nε-(3-formyl-3,4-dehydropiperidino)lysineGRP, glucose regulated proteinGSTP, glutathione-s-transferase-PiIRE1, inositol-requiring enzyme 1JNK, cJun N-terminal kinaseLPO, lipid peroxidationLipid PeroxidationNIAAA, National Institute on Alcohol Abuse and AlcoholismPERK, protein kinase RNA-like endoplasmic reticulum kinasePUFA, polyunsaturated fatty acidsTRAF, TNF receptor-associated factorTUNEL, terminal deoxynucleotidyl transferase–mediated deoxyuridine triphosphate nick-end labelingTherapeuticUPR, unfolded protein responseXBP1, X-box binding protein-1mRNA, messenger RNAsiRNA, small interfering RNA
DOI
10.1016/j.jcmgh.2016.05.010
PMID
28119953
发布时间
2019-11-20
- 浏览8
Cellular and molecular gastroenterology and hepatology
2016年2卷5期
685-700页
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