Epigenetic silencing of XAF1 in high-grade gliomas is associated with IDH1 status and improved clinical outcome.
第一作者:
Thomas R,Reich
第一单位:
Department of Toxicology, University Medical Center, D-55131 Mainz, Germany.
作者:
主题词
衔接蛋白质类, 信号转导(Adaptor Proteins, Signal Transducing);老年人(Aged);细胞凋亡(Apoptosis);凋亡调节蛋白质类(Apoptosis Regulatory Proteins);脑肿瘤(Brain Neoplasms);细胞增殖(Cell Proliferation);DNA甲基化(DNA Methylation);后成说, 遗传(Epigenesis, Genetic);女(雌)性(Female);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);基因沉默(Gene Silencing);神经胶质瘤(Glioma);人类(Humans);细胞内信号肽和蛋白质类(Intracellular Signaling Peptides and Proteins);异柠檬酸脱氢酶(Isocitrate Dehydrogenase);男(雄)性(Male);突变(Mutation);肿瘤蛋白质类(Neoplasm Proteins);预后(Prognosis);启动区, 遗传(Promoter Regions, Genetic);存活率(Survival Rate);肿瘤细胞, 培养的(Tumor Cells, Cultured)
DOI
10.18632/oncotarget.14748
PMID
28122345
发布时间
2020-12-09
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Oncotarget
15071-15084页
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