A G1-like state allows HIV-1 to bypass SAMHD1 restriction in macrophages.

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作者： Petra,Mlcochova ^[1] ; Katherine A,Sutherland ^[1] ; Sarah A,Watters ^[1] ; Cosetta,Bertoli ^[2] ; Rob Am,de Bruin ^[2] ; Jan,Rehwinkel ^[3] ; Stuart J,Neil ^[4] ; Gina M,Lenzi ^[5] ; Baek,Kim ^[5] ; Asim,Khwaja ^[6] ; Matthew C,Gage ^[7] ; Christiana,Georgiou ^[7] ; Alexandra,Chittka ^[7] ; Simon,Yona ^[7] ; Mahdad,Noursadeghi ^[1] ; Greg J,Towers ^[1] ; Ravindra K,Gupta ^[8]

作者单位： Division of Infection and Immunity, University College London, London, UK. ^[1] MRC Laboratory for Molecular Cell Biology, University College London, London, UK. ^[2] Medical Research Council Human Immunology Unit, Radcliffe Department of Medicine, Medical Research Council Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK. ^[3] Division of Immunology, Infection and Inflammatory Disease, King's College, London, UK. ^[4] Department of Pediatrics, Center for Drug Discovery, Emory School of Medicine, Atlanta, GA, USA. ^[5] Research Department of Haematology, UCL, London, UK. ^[6] Division of Medicine, University College London, London, UK. ^[7] Division of Infection and Immunity, University College London, London, UK ravindra.gupta@ucl.ac.uk. ^[8] Africa Health Research Institute, KwaZulu Natal, South Africa. ^[9]

关键词 HIV SAMHD1 cell cycle histone deacetylase macrophage