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首页> Journal of medicinal chemistry> Accepting the Invitation to Open Innovation in Malaria Drug Discovery: Synthesis, Biological Evaluation, and Investigation on the Structure-Activity Relationships of Benzo[b]thiophene-2-carboxamides as Antimalarial Agents.

Accepting the Invitation to Open Innovation in Malaria Drug Discovery: Synthesis, Biological Evaluation, and Investigation on the Structure-Activity Relationships of Benzo[b]thiophene-2-carboxamides as Antimalarial Agents.

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作者： Marco,Pieroni ^[1] ; Elisa,Azzali ^[2] ; Nicoletta,Basilico ^[3] ; Silvia,Parapini ^[4] ; Michal,Zolkiewski ; Claudia,Beato ; Giannamaria,Annunziato ; Agostino,Bruno ; Federica,Vacondio ; Gabriele,Costantino

作者单位： Dipartimento di Scienze Biomediche, Chirurgiche e Odontoiatriche, Università di Milano , via Pascal 36, Milano 20133, Italy. ^[1] Dipartimento di Scienze Farmacologiche e Biomolecolari, Università di Milano , via Pascal 36, Milano 20133, Italy. ^[2] Department of Biochemistry and Molecular Biophysics, Kansas State University , Manhattan, Kansas 66506, United States. ^[3] Centro Interdipartimentale Misure (CIM) 'G. Casnati', University of Parma , Parco Area delle Scienze 23/A, 43124 Parma, Italy. ^[4]

主题词酰胺类(Amides);抗疟药(Antimalarials);药物发现(Drug Discovery);药物评价, 临床前(Drug Evaluation, Preclinical);人类(Humans);构效关系(Structure-Activity Relationship);噻吩类(Thiophenes)

DOI 10.1021/acs.jmedchem.6b01685

PMID 28128956

发布时间 2018-11-04

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准确一般字义偏差语意偏离译文作用小提交

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Journal of medicinal chemistry

Journal of medicinal chemistry

2017年60卷5期

1959-1970页

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