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Hypothyroidism in utero stimulates pancreatic beta cell proliferation and hyperinsulinaemia in the ovine fetus during late gestation.

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第一作者： Shelley E,Harris

第一单位： Department of Biological and Medical Sciences, Oxford Brookes University, Oxford, OX3 0BP, UK.

作者： Shelley E,Harris ^[1] ; Miles J,De Blasio ^[2] ; Melissa A,Davis ^[3] ; Amy C,Kelly ^[3] ; Hailey M,Davenport ^[3] ; F B Peter,Wooding ^[2] ; Dominique,Blache ^[4] ; David,Meredith ^[1] ; Miranda,Anderson ^[3] ; Abigail L,Fowden ^[2] ; Sean W,Limesand ^[3] ; Alison J,Forhead ^[5]

作者单位： Department of Biological and Medical Sciences, Oxford Brookes University, Oxford, OX3 0BP, UK. ^[1] Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, CB2 3EG, UK. ^[2] School of Animal and Comparative Biomedical Sciences, University of Arizona, Tucson, AZ, 85721, USA. ^[3] School of Animal Biology, University of Western Australia, 6009, Crawley, Australia. ^[4] Department of Biological and Medical Sciences, Oxford Brookes University, Oxford, OX3 0BP, UK.;Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, CB2 3EG, UK. ^[5]

关键词 fetal programming insulin islet cell pancreas thyroid hormone