Caffeic Acid Cyclohexylamide Rescues Lethal Inflammation in Septic Mice through Inhibition of IκB Kinase in Innate Immune Process.

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作者： Jun Hyeon,Choi ^[1] ; Sun Hong,Park ^[1] ; Jae-Kyung,Jung ^[1] ; Won-Jea,Cho ^[2] ; Byeongwoo,Ahn ^[3] ; Cheong-Yong,Yun ^[1] ; Yong Pyo,Choi ^[1] ; Jong Hun,Yeo ^[1] ; Heesoon,Lee ^[1] ; Jin Tae,Hong ^[1] ; Sang-Bae,Han ^[1] ; Youngsoo,Kim ^[1]

作者单位： College of Pharmacy, Chungbuk National University, Cheongju 362-763, Korea. ^[1] College of Pharmacy, Chonnam National University, Gwangju 500-757, Korea. ^[2] College of Veterinary Medicine, Chungbuk National University, Cheongju 362-763, Korea. ^[3]

主题词动物(Animals);消炎药(Anti-Inflammatory Agents);结合部位(Binding Sites);咖啡酸类(Caffeic Acids);环己胺类(Cyclohexylamines);疾病模型, 动物(Disease Models, Animal);半乳糖胺(Galactosamine);基因表达调控(Gene Expression Regulation);I-κB激酶(I-kappa B Kinase);脂多糖类(Lipopolysaccharides);肝功能衰竭, 急性(Liver Failure, Acute);男(雄)性(Male);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);模型, 分子(Models, Molecular);磷酰化(Phosphorylation);休克, 脓毒性(Shock, Septic)

DOI 10.1038/srep41180

PMID 28145460

发布时间 2018-11-13

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Caffeic Acid Cyclohexylamide Rescues Lethal Inflammation in Septic Mice through Inhibition of IκB Kinase in Innate Immune Process.

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Caffeic Acid Cyclohexylamide Rescues Lethal Inflammation in Septic Mice through Inhibition of IκB Kinase in Innate Immune Process.

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