MAPK pathway inhibition induces MET and GAB1 levels, priming BRAF mutant melanoma for rescue by hepatocyte growth factor.
第一作者:
Sean,Caenepeel
第一单位:
Department of Oncology Research, Amgen, Inc., Thousand Oaks, CA, USA.
作者:
医学主题词
衔接蛋白质类, 信号转导(Adaptor Proteins, Signal Transducing);动物(Animals);抗肿瘤药(Antineoplastic Agents);细胞凋亡(Apoptosis);苯甲酰胺类(Benzamides);细胞系, 肿瘤(Cell Line, Tumor);二肽类(Dipeptides);二苯胺(Diphenylamine);抗药性, 肿瘤(Drug Resistance, Neoplasm);女(雌)性(Female);肝细胞生长因子(Hepatocyte Growth Factor);人类(Humans);吲哚类(Indoles);MAP激酶信号系统(MAP Kinase Signaling System);黑色素瘤(Melanoma);小鼠(Mice);小鼠, 裸(Mice, Nude);蛋白激酶抑制剂(Protein Kinase Inhibitors);原癌基因蛋白质B-raf(Proto-Oncogene Proteins B-raf);原癌基因蛋白质c-met(Proto-Oncogene Proteins c-met);吡啶酮类(Pyridones);磺胺类(Sulfonamides);三唑类(Triazoles);异种移植模型抗肿瘤试验(Xenograft Model Antitumor Assays)
DOI
10.18632/oncotarget.14855
PMID
28147313
发布时间
2021-09-29
- 浏览40
Oncotarget
17795-17809页
相似文献
- 中文期刊
- 外文期刊
- 学位论文
- 会议论文


换一批



