Reduced Potency and Incomplete Neutralization of Broadly Neutralizing Antibodies against Cell-to-Cell Transmission of HIV-1 with Transmitted Founder Envs.

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第一作者： Hongru,Li

第一单位： Microbiology Graduate School Training Program, Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.;Division of Infectious Disease, Department of Medicine, Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

作者： Hongru,Li ^[1] ; Chati,Zony ^[1] ; Ping,Chen ^[2] ; Benjamin K,Chen ^[3]

作者单位： Microbiology Graduate School Training Program, Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.;Division of Infectious Disease, Department of Medicine, Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA. ^[1] Division of Infectious Disease, Department of Medicine, Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA. ^[2] Microbiology Graduate School Training Program, Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, USA ben.chen@mssm.edu.;Division of Infectious Disease, Department of Medicine, Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA. ^[3]

关键词 HIV-1 envelope (Env)broadly neutralizing antibodies (bNAbs)cell-to-cell infection efficacy human immunodeficiency virus subtype 1 (HIV-1)incomplete neutralization maximum neutralization potency tyrosine-based sorting motif virological synapse (VS)