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In search of new α-glucosidase inhibitors: Imidazolylpyrazole derivatives.

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第一作者： Faryal,Chaudhry

第一单位： Institute of Chemistry, University of the Punjab, Lahore 54590, Pakistan; Department of Chemistry, Kinnaird College for Women, Lahore 54000, Pakistan.

作者： Faryal,Chaudhry ^[1] ; Sadia,Naureen ^[2] ; Rahila,Huma ^[3] ; Ayesha,Shaukat ^[4] ; Mariya,Al-Rashida ^[5] ; Nadia,Asif ^[2] ; Mohammad,Ashraf ^[6] ; Munawar Ali,Munawar ^[7] ; Misbahul Ain,Khan ^[8]

作者单位： Institute of Chemistry, University of the Punjab, Lahore 54590, Pakistan; Department of Chemistry, Kinnaird College for Women, Lahore 54000, Pakistan. ^[1] Institute of Chemistry, University of the Punjab, Lahore 54590, Pakistan. ^[2] Department of Chemistry, Kinnaird College for Women, Lahore 54000, Pakistan. ^[3] Department of Biochemistry and Biotechnology, The Islamia University of Bahawalpur, Bahawalpur 63100, Pakistan. ^[4] Department of Chemistry, Forman Christian College (A Chartered University), Ferozepur Road, Lahore 54600, Pakistan. ^[5] Department of Chemistry, The Islamia University of Bahawalpur, Bahawalpur 63100, Pakistan. ^[6] Institute of Chemistry, University of the Punjab, Lahore 54590, Pakistan. Electronic address: mamunawar.chem@pu.edu.pk. ^[7] Institute of Chemistry, University of the Punjab, Lahore 54590, Pakistan; Department of Chemistry, The Islamia University of Bahawalpur, Bahawalpur 63100, Pakistan. ^[8]

关键词 Diabetes Docking Imidazolylpyrazoles Multicomponent reaction α-Glucosidase inhibition

医学主题词糖尿病, 2型(Diabetes Mellitus, Type 2);人类(Humans);吡唑类(Pyrazoles);酿酒酵母菌(Saccharomyces cerevisiae);构效关系(Structure-Activity Relationship);α葡糖苷酶类(alpha-Glucosidases)

DOI 10.1016/j.bioorg.2017.01.017

PMID 28160945

发布时间 2020-12-09

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