换一批
换一批Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia.
作者：
Philip J,Law [1]
;
Sonja I,Berndt [2]
;
Helen E,Speedy [1]
;
Nicola J,Camp [3]
;
Georgina P,Sava [1]
;
Christine F,Skibola [4]
;
Amy,Holroyd [1]
;
Vijai,Joseph [5]
;
Nicola J,Sunter [6]
;
Alexandra,Nieters [7]
;
Silvia,Bea [8]
;
Alain,Monnereau [9]
;
David,Martin-Garcia [10]
;
Lynn R,Goldin [11]
;
Guillem,Clot [8]
;
Lauren R,Teras [2]
;
Inés,Quintela [8]
;
Brenda M,Birmann [12]
;
Sandrine,Jayne [13]
;
Wendy,Cozen [14]
;
Aneela,Majid [15]
;
Karin E,Smedby [16]
;
Qing,Lan [17]
;
Claire,Dearden [15]
;
Angela R,Brooks-Wilson [18]
;
Andrew G,Hall [2]
;
Mark P,Purdue [19]
;
Tryfonia,Mainou-Fowler [20]
;
Claire M,Vajdic [21]
;
Graham H,Jackson [6]
;
Pierluigi,Cocco [2]
;
Helen,Marr [22]
;
Yawei,Zhang [23]
;
Tongzhang,Zheng [24]
;
Graham G,Giles [25]
;
Charles,Lawrence [6]
;
Timothy G,Call [26]
;
Mark,Liebow [26]
;
Mads,Melbye [27]
;
Bengt,Glimelius [28]
;
Larry,Mansouri [29]
;
Martha,Glenn [30]
;
Karen,Curtin [31]
;
W Ryan,Diver [32]
;
Brian K,Link [33]
;
Lucia,Conde [34]
;
Paige M,Bracci [34]
;
Elizabeth A,Holly [3]
;
Rebecca D,Jackson [3]
;
Lesley F,Tinker [12]
;
Yolanda,Benavente [35]
;
Paolo,Boffetta [4]
;
Paul,Brennan [36]
;
Marc,Maynadie [36]
;
James,McKay [37]
;
Demetrius,Albanes [38]
;
Stephanie,Weinstein [39]
;
Zhaoming,Wang [40]
;
Neil E,Caporaso [41]
;
Lindsay M,Morton [42]
;
Richard K,Severson [43]
;
Elio,Riboli [42]
;
Paolo,Vineis [2]
;
Roel C H,Vermeulen [2]
;
Melissa C,Southey [44]
;
Roger L,Milne [2]
;
Jacqueline,Clavel [2]
;
Sabine,Topka [45]
;
John J,Spinelli [46]
;
Peter,Kraft [47]
;
Maria Grazia,Ennas [48]
;
Geoffrey,Summerfield [49]
;
Giovanni M,Ferri [50]
;
Robert J,Harris [51]
;
Lucia,Miligi [27]
;
Andrew R,Pettitt [28]
;
Kari E,North [52]
;
David J,Allsup [53]
;
Joseph F,Fraumeni [5]
;
James R,Bailey [54]
;
Kenneth,Offit [55]
;
Guy,Pratt [56]
;
Henrik,Hjalgrim [57]
;
Chris,Pepper [58]
;
Stephen J,Chanock [59]
;
Chris,Fegan [60]
;
Richard,Rosenquist [61]
;
Silvia,de Sanjose [62]
;
Angel,Carracedo [61]
;
Martin J S,Dyer [63]
;
Daniel,Catovsky [64]
;
Elias,Campo [65]
;
James R,Cerhan [2]
;
James M,Allan [65]
;
Nathanial,Rothman [5]
;
Richard,Houlston [66]
;
Susan,Slager [32]
作者单位：
Division of Genetics and Epidemiology, The Institute of Cancer Research, London SW7 3RP, UK.
[1]
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892, USA.
[2]
Department of Internal Medicine, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, Utah 84112, USA.
[3]
Department of Epidemiology, School of Public Health and Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, Alabama 35233, USA.
[4]
Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.
[5]
Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne NE2 4HH, UK.
[6]
Center for Chronic Immunodeficiency, University Medical Center Freiburg, Freiburg, Baden-Württemberg 79108, Germany.
[7]
Institut d'Investigacions Biomèdiques August Pi iSunyer (IDIBAPS), Hospital Clínic, Barcelona 08036, Spain.
[8]
Registre des hémopathies malignes de la Gironde, Institut Bergonié, Inserm U1219 EPICENE, 33076 Bordeaux, France.
[9]
Epidemiology of Childhood and Adolescent Cancers Group, Inserm, Center of Research in Epidemiology and Statistics Sorbonne Paris Cité, Paris, F-94807, France.
[10]
Université Paris Descartes, Paris 75270, France.
[11]
Epidemiology Research Program, American Cancer Society, Atlanta, Georgia 30303, USA.
[12]
Grupo de Medicina Xenomica, Universidade de Santiago de Compostela, Centro Nacional de Genotipado (CeGen-PRB2-ISCIII), CIBERER, 15782 Santiago de Compostela, Spain.
[13]
Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.
[14]
Ernest and Helen Scott Haematological Research Institute, University of Leicester, Leicester LE2 7LX, UK.
[15]
Department of Preventive Medicine, USC Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA.
[16]
Norris Comprehensive Cancer Center, USC Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA.
[17]
Unit of Clinical Epidemiology, Department of Medicine Solna, Karolinska Institutet, Hematology Center, Karolinsak University Hospital, Stockholm 17176, Sweden.
[18]
The Royal Marsden NHS Foundation Trust, London SM2 5PT, UK.
[19]
Genome Sciences Centre, BC Cancer Agency, Vancouver, British Columbia, Canada V5Z1L3.
[20]
Department of Biomedical Physiology and Kinesiology, Simon Fraser University, Burnaby, British Columbia V5A1S6, Canada.
[21]
Haematological Sciences, Medical School, Newcastle University, Newcastle-upon-Tyne NE2 4HH, UK.
[22]
Centre for Big Data Research in Health, University of New South Wales, Sydney, New South Wales 2052, Australia.
[23]
Department of Haematology, Royal Victoria Infirmary, Newcastle upon Tyne NE1 4LP, UK.
[24]
Department of Public Health, Clinical and Molecular Medicine, University of Cagliari, Monserrato, Cagliari 09042, Italy.
[25]
Department of Environmental Health Sciences, Yale School of Public Health, New Haven, Connecticut 06520, USA.
[26]
Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, Victoria 3004, Australia.
[27]
Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Victoria 3010, Australia.
[28]
Westat, Rockville, Maryland 20850, USA.
[29]
Division of Hematology, Mayo Clinic, Rochester, Minnesota 55905, USA.
[30]
Department of Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA.
[31]
Department of Epidemiology Research, Division of Health Surveillance and Research, Statens Serum Institut, 2300 Copenhagen, Denmark.
[32]
Department of Medicine, Stanford University School of Medicine, Stanford, California 94305, USA.
[33]
Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, 75105 Uppsala, Sweden.
[34]
Department of Internal Medicine, Carver College of Medicine, The University of Iowa, Iowa City, Iowa 52242, USA.
[35]
Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California 94118, USA.
[36]
Division of Endocrinology, Diabetes and Metabolism, Ohio State University, Columbus, Ohio 43210, USA.
[37]
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98117, USA.
[38]
Cancer Epidemiology Research Programme, Catalan Institute of Oncology-IDIBELL, L'Hospitalet de Llobregat, Barcelona 08908, Spain.
[39]
CIBER de Epidemiología y Salud Pública (CIBERESP), Barcelona 08036, Spain.
[40]
The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.
[41]
International Agency for Research on Cancer, Lyon 69372, France.
[42]
Registre des Hémopathies Malignes de Côte d'Or, University of Burgundy and Dijon University Hospital, Dijon 21070, France.
[43]
Department of Computational Biology, St Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.
[44]
Department of Family Medicine and Public Health Sciences, Wayne State University, Detroit, Michigan 48201, USA.
[45]
School of Public Health, Imperial College London, London W2 1PG, UK.
[46]
MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London W2 1PG, UK.
[47]
Human Genetics Foundation, 10126 Turin, Italy.
[48]
Institute for Risk Assessment Sciences, Utrecht University, Utrecht 3508 TD, The Netherlands.
[49]
Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht 3584 CX, The Netherlands.
[50]
Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne, Melbourne, Victoria 3010, Australia.
[51]
Epidemiology of Childhood and Adolescent Cancers Group, Inserm, Center of Research in Epidemiology and Statistics Sorbonne Paris Cité (CRESS), Paris F-94807, France.
[52]
Université Paris Descartes, 75270 Paris, France.
[53]
Cancer Control Research, BC Cancer Agency, Vancouver, British Columbia, Canada V5Z1L3.
[54]
School of Population and Public Health, University of British Columbia, Vancouver, British Columbia, Canada V6T1Z3.
[55]
Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA.
[56]
Department of Biostatistics, Harvard T. H. Chan School of Public Health, Boston, Massachusetts 02115, USA.
[57]
Department of Biomedical Science, University of Cagliari, Monserrato, Cagliari 09042, Italy.
[58]
Department of Haematology, Queen Elizabeth Hospital, Gateshead NE9 6SX, UK.
[59]
Interdisciplinary Department of Medicine, University of Bari, Bari 70124, Italy.
[60]
Department of Molecular and Clinical Cancer Medicine, University of Liverpool, Liverpool L69 3BX, UK.
[61]
Environmental and Occupational Epidemiology Unit, Cancer Prevention and Research Institute (ISPO), Florence 50139, Italy.
[62]
Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA.
[63]
Carolina Center for Genome Sciences, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA.
[64]
Queens Centre for Haematology and Oncology, Castle Hill Hospital, Hull and East Yorkshire NHS Trust, Cottingham HU16 5JQ, UK.
[65]
Department of Haematology, Birmingham Heartlands Hospital, Birmingham B9 5SS, UK.
[66]
Division of Cancer and Genetics, School of Medicine, Cardiff University, Cardiff CF14 4XN, UK.
[67]
Cardiff and Vale National Health Service Trust, Heath Park, Cardiff CF14 4XW, UK.
[68]
Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah 21589, KSA.
[69]
Division of Molecular Pathology, The Institute of Cancer Research, London SW7 3RP, UK.
[70]
Unitat de Hematología, Hospital Clínic, IDIBAPS, Universitat de Barcelona, Barcelona 08036, Spain.
[71]
Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55905, USA.
[72]
主题词
成年人(Adult);抗体生成(Antibody Formation);B-淋巴细胞(B-Lymphocytes);病例对照研究(Case-Control Studies);染色体图(Chromosome Mapping);染色体, 人(Chromosomes, Human);女(雌)性(Female);疾病遗传易感性(Genetic Predisposition to Disease);全基因组关联研究(Genome-Wide Association Study);人类(Humans);白血病, 淋巴细胞, 慢性, B细胞(Leukemia, Lymphocytic, Chronic, B-Cell);男(雄)性(Male);中年人(Middle Aged);多态性, 单核苷酸(Polymorphism, Single Nucleotide);青年人(Young Adult)
DOI
10.1038/ncomms14175
PMID
28165464
发布时间
2024-07-15
- 浏览12
Nature communications
14175页
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