Design and Synthesis of Novel and Selective Phosphodiesterase 2 (PDE2a) Inhibitors for the Treatment of Memory Disorders.

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作者： Laurent,Gomez ^[1] ; Mark Eben,Massari ^[1] ; Troy,Vickers ^[1] ; Graeme,Freestone ^[1] ; William,Vernier ^[1] ; Kiev,Ly ^[1] ; Rui,Xu ^[1] ; Margaret,McCarrick ^[1] ; Tami,Marrone ^[1] ; Markus,Metz ^[1] ; Yingzhou G,Yan ^[1] ; Zachary W,Yoder ^[1] ; Robert,Lemus ^[1] ; Nicola J,Broadbent ^[1] ; Richard,Barido ^[1] ; Noelle,Warren ^[1] ; Kara,Schmelzer ^[1] ; David,Neul ^[1] ; Dong,Lee ^[1] ; Carsten B,Andersen ^[1] ; Kristen,Sebring ^[1] ; Kathleen,Aertgeerts ^[1] ; Xianbo,Zhou ^[1] ; Ali,Tabatabaei ^[1] ; Marco,Peters ^[1] ; J Guy,Breitenbucher ^[1]

作者单位： Dart Neuroscience LLC, 12278 Scripps Summit Drive, San Diego, California 92131, United States. ^[1]

主题词色谱法, 液相(Chromatography, Liquid);外切核酸酶类(Exonucleases);人类(Humans);记忆障碍(Memory Disorders);磷酸二酯酶抑制剂(Phosphodiesterase Inhibitors)

DOI 10.1021/acs.jmedchem.6b01793

PMID 28165743

发布时间 2018-11-04

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准确一般字义偏差语意偏离译文作用小提交