Oligonucleotide-Lipid Conjugates Forming G-Quadruplex Structures Are Potent and Pangenotypic Hepatitis C Virus Entry Inhibitors <i>In Vitro</i> and <i>Ex Vivo</i>.

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作者： George,Koutsoudakis ; Alexia,Paris de León ; Carolina,Herrera ; Marcus,Dorner ; Gemma,Pérez-Vilaró ; Sébastien,Lyonnais ; Santiago,Grijalvo ; Ramon,Eritja ; Andreas,Meyerhans ; Gilles,Mirambeau ; Juana,Díez

关键词 DNA G-quadruplex structures HCV cell-to-cell inhibitor HCV entry inhibitor HCV pangenotypic inhibitor antiviral treatment oligonucleotide-cholesterol conjugates

主题词抗病毒药(Antiviral Agents);细胞系, 肿瘤(Cell Line, Tumor);胆固醇(Cholesterol);G四链体(G-Quadruplexes);HEK293细胞(HEK293 Cells);HIV感染(HIV Infections);肝炎病毒属(Hepacivirus);丙型肝炎(Hepatitis C);同性恋, 男性(Homosexuality, Male);人类(Humans);男(雄)性(Male);寡核苷酸类(Oligonucleotides);病毒内化(Virus Internalization)

DOI 10.1128/AAC.02354-16

PMID 28193659

发布时间 2024-10-09

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Antimicrobial agents and chemotherapy

2017年61卷5期

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Oligonucleotide-Lipid Conjugates Forming G-Quadruplex Structures Are Potent and Pangenotypic Hepatitis C Virus Entry Inhibitors <i>In Vitro</i> and <i>Ex Vivo</i>.

Antimicrobial agents and chemotherapy

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Antimicrobial agents and chemotherapy

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Oligonucleotide-Lipid Conjugates Forming G-Quadruplex Structures Are Potent and Pangenotypic Hepatitis C Virus Entry Inhibitors <i>In Vitro</i> and <i>Ex Vivo</i>.

Antimicrobial agents and chemotherapy

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Antimicrobial agents and chemotherapy

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