Enhancing VTA Ca<sub>v</sub>1.3 L-type Ca<sup>2+</sup> channel activity promotes cocaine and mood-related behaviors via overlapping AMPA receptor mechanisms in the nucleus accumbens.
第一作者:
A,Martínez-Rivera
第一单位:
Division of Pediatric Neurology, Department of Pediatrics, Weill Cornell Medicine, New York, NY, USA.;Feil Family Brain and Mind Research Institute, Weill Cornell Medical College, New York, NY, USA.
作者:
医学主题词
情感(Affect);动物(Animals);钙通道, L型(Calcium Channels, L-Type);可卡因(Cocaine);可卡因相关性障碍(Cocaine-Related Disorders);抑郁(Depression);疾病模型, 动物(Disease Models, Animal);多巴胺摄取抑制剂(Dopamine Uptake Inhibitors);遗传关联研究(Genetic Association Studies);人类(Humans);男(雄)性(Male);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 转基因(Mice, Transgenic);运动活动(Motor Activity);伏核(Nucleus Accumbens);突触后密度(Post-Synaptic Density);受体, AMPA(Receptors, AMPA);社会行为(Social Behavior);腹侧被盖区(Ventral Tegmental Area)
DOI
10.1038/mp.2017.9
PMID
28194001
发布时间
2025-05-30
- 浏览20
Molecular psychiatry
1735-1745页
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