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首页> Neuroscience letters> A pilot study of cell-mediated gene therapy for spinal cord injury in mini pigs.

A pilot study of cell-mediated gene therapy for spinal cord injury in mini pigs.

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作者： Rustem Robertovich,Islamov ^[1] ; Mikhail Evgenyevich,Sokolov ^[2] ; Farid Vagizovich,Bashirov ^[1] ; Filip Olegovich,Fadeev ^[2] ; Maxim Michaylovich,Shmarov ^[3] ; Boris Savelyevich,Naroditskiy ^[3] ; Tatyana Vyacheslavovna,Povysheva ^[1] ; Gulnara Ferdinantovna,Shaymardanova ^[1] ; Radik Albertovich,Yakupov ^[4] ; Yuri Aleksandrovich,Chelyshev ^[2] ; Igor Aleksandrovich,Lavrov ^[5]

作者单位： Kazan State Medical University, Kazan, Russia. ^[1] Kazan State Medical University, Kazan, Russia; Kazan Federal University, Kazan, Russia. ^[2] Gamaleya Research Institute of Epidemiology and Microbiology, Moscow, Russia. ^[3] Kazan State Medical Academy, Kazan, Russia. ^[4] Kazan Federal University, Kazan, Russia; Departments of Neurologic Surgery and Biomedical Engineering, Mayo Clinic, Rochester, MN, United States. Electronic address: lavrov.igor@mayo.edu. ^[5]

关键词 Adenoviral vector Cell-mediated gene therapy Glial cell-derived neurotrophic factor (GDNF)Human umbilical cord blood mononuclear cell Mini pigs Neural cell adhesion molecule (NCAM)Spinal cord injury Vascular endothelial growth factor (VEGF)

主题词腺病毒科(Adenoviridae);动物(Animals);脐血干细胞移植(Cord Blood Stem Cell Transplantation);疾病模型, 动物(Disease Models, Animal);女(雌)性(Female);遗传载体(Genetic Vectors);胶质细胞源性神经营养因子(Glial Cell Line-Derived Neurotrophic Factor);人类(Humans);白细胞, 单核(Leukocytes, Mononuclear);神经细胞黏附分子类(Neural Cell Adhesion Molecules);试点项目(Pilot Projects);功能恢复(Recovery of Function);脊髓损伤(Spinal Cord Injuries);猪(Swine);猪, 雏型(Swine, Miniature);血管内皮生长因子A(Vascular Endothelial Growth Factor A)

DOI 10.1016/j.neulet.2017.02.034

PMID 28213069

发布时间 2018-08-27

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Neuroscience letters

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