首页> Journal of experimental & clinical cancer research : CR> Che-1 sustains hypoxic response of colorectal cancer cells by affecting Hif-1α stabilization.

Che-1 sustains hypoxic response of colorectal cancer cells by affecting Hif-1α stabilization.

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第一作者： Tiziana,Bruno

第一单位： UOSD SAFU, Department of Research, Diagnosis and Innovative Technologies, Translational Research Area, Regina Elena National Cancer Institute, Via E. Chianesi 53, 00144, Rome, Italy. tiziana.bruno@ifo.gov.it.

作者： Tiziana,Bruno ^[1] ; Mariacristina,Valerio ^[2] ; Luca,Casadei ^[2] ; Francesca,De Nicola ^[3] ; Frauke,Goeman ^[4] ; Matteo,Pallocca ^[3] ; Valeria,Catena ^[3] ; Simona,Iezzi ^[3] ; Cristina,Sorino ^[3] ; Agata,Desantis ^[3] ; Cesare,Manetti ^[2] ; Giovanni,Blandino ^[4] ; Aristide,Floridi ^[3] ; Maurizio,Fanciulli ^[5]

作者单位： UOSD SAFU, Department of Research, Diagnosis and Innovative Technologies, Translational Research Area, Regina Elena National Cancer Institute, Via E. Chianesi 53, 00144, Rome, Italy. tiziana.bruno@ifo.gov.it. ^[1] Department of Chemistry, "Sapienza" University, Rome, Italy. ^[2] UOSD SAFU, Department of Research, Diagnosis and Innovative Technologies, Translational Research Area, Regina Elena National Cancer Institute, Via E. Chianesi 53, 00144, Rome, Italy. ^[3] UOSD Oncogenomic and Epigenetic Unit, Regina Elena National Cancer Institute, Rome, Italy. ^[4] UOSD SAFU, Department of Research, Diagnosis and Innovative Technologies, Translational Research Area, Regina Elena National Cancer Institute, Via E. Chianesi 53, 00144, Rome, Italy. maurizio.fanciulli@ifo.gov.it. ^[5]

关键词 Che-1/AATF HIF-1α Hypoxia Metabolism PHD3/EGLN3 SIAH-2