USP7 inhibitor P5091 inhibits Wnt signaling and colorectal tumor growth.

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作者： Tao,An ^[1] ; Yaxiao,Gong ^[1] ; Xue,Li ^[1] ; Lingmei,Kong ^[1] ; Pengcheng,Ma ^[2] ; Liang,Gong ^[1] ; Huifang,Zhu ^[1] ; Chunlei,Yu ^[1] ; Jianmei,Liu ^[1] ; Hongyu,Zhou ^[3] ; Bingyu,Mao ^[2] ; Yan,Li ^[4]

作者单位： State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, China; University of Chinese Academy of Sciences, Beijing, China. ^[1] State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China. ^[2] State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, China. ^[3] State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, China. Electronic address: liyanb@mail.kib.ac.cn. ^[4]

关键词 Colorectal cancer USP7 inhibitor Wnt signaling

主题词细胞系, 肿瘤(Cell Line, Tumor);细胞增殖(Cell Proliferation);结直肠肿瘤(Colorectal Neoplasms);HEK293细胞(HEK293 Cells);人类(Humans);预后(Prognosis);信号传导(Signal Transduction);噻吩类(Thiophenes);转录, 遗传(Transcription, Genetic);泛素硫酯酶(Ubiquitin Thiolesterase);泛素化(Ubiquitination);Wnt蛋白质类(Wnt Proteins);β连环素(beta Catenin)

DOI 10.1016/j.bcp.2017.02.011

PMID 28216017

发布时间 2022-03-31

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Biochemical pharmacology

2017年131卷

29-39页

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USP7 inhibitor P5091 inhibits Wnt signaling and colorectal tumor growth.

Biochemical pharmacology

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Biochemical pharmacology

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USP7 inhibitor P5091 inhibits Wnt signaling and colorectal tumor growth.

Biochemical pharmacology

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Biochemical pharmacology

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