BECN2 interacts with ATG14 through a metastable coiled-coil to mediate autophagy.

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作者： Minfei,Su ^[1] ; Yue,Li ^[1] ; Shane,Wyborny ^[1] ; David,Neau ^[2] ; Srinivas,Chakravarthy ^[3] ; Beth,Levine ^[4] ; Christopher L,Colbert ^[1] ; Sangita C,Sinha ^[1]

作者单位： Department of Chemistry and Biochemistry, North Dakota State University, Fargo, North Dakota, 58108-6050. ^[1] Department of Chemistry and Chemical Biology, Cornell University, Northeastern Collaborative Access Team, Argonne National Laboratory, Argonne, Illinois, 60439. ^[2] Biophysics Collaborative Access Team/Illinois Institute of Technology, Advanced Photon Source, Argonne National Laboratory, Argonne, Illinois, 60439. ^[3] Center for Autophagy Research, Department of Internal Medicine and Howard Hughes Medical Research Institute, University of Texas Southwestern Medical Center, Dallas, Texas, 75390. ^[4]

关键词 ATG14 BECN2 BECN2:ATG14 heterodimer autophagy coiled-coil domain

主题词衔接蛋白质类, 膜泡运输(Adaptor Proteins, Vesicular Transport);自噬(Autophagy);人类(Humans);细胞内信号肽和蛋白质类(Intracellular Signaling Peptides and Proteins);蛋白质多聚化(Protein Multimerization);蛋白质结构, 四级(Protein Structure, Quaternary);蛋白质结构, 二级(Protein Structure, Secondary)

DOI 10.1002/pro.3140

PMID 28218432

发布时间 2024-09-22

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