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首页> Proceedings of the National Academy of Sciences of the United States of America> Intragenic CpG islands play important roles in bivalent chromatin assembly of developmental genes.

Intragenic CpG islands play important roles in bivalent chromatin assembly of developmental genes.

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作者： Sun-Min,Lee ^[1] ; Jungwoo,Lee ^[2] ; Kyung-Min,Noh ^[3] ; Won-Young,Choi ^[2] ; Sejin,Jeon ^[4] ; Goo Taeg,Oh ^[4] ; Jeongsil,Kim-Ha ^[5] ; Yoonhee,Jin ^[6] ; Seung-Woo,Cho ^[6] ; Young-Joon,Kim ^[7]

作者单位： Department of Biochemistry, College of Life Science and Technology, Yonsei University, Seoul 03722, Republic of Korea. ^[1] Department of Integrated Omics for Biomedical Science, Graduate School, Yonsei University, Seoul 03722, Republic of Korea. ^[2] Genome Biology Unit, European Molecular Biology Laboratory, 69117 Heidelberg, Germany. ^[3] Department of Life Sciences, Ewha Womans University, Seoul 03760, Republic of Korea. ^[4] Department of Integrative Bioscience and Biotechnology, College of Life Sciences, Sejong University, Seoul 05006, Republic of Korea. ^[5] Department of Biotechnology, College of Life Science and Technology, Yonsei University, Seoul 03722, Republic of Korea. ^[6] Department of Biochemistry, College of Life Science and Technology, Yonsei University, Seoul 03722, Republic of Korea; yjkim@yonsei.ac.kr. ^[7]

关键词 DNA methylation bivalent chromatin differentiation embryonic stem cell intragenic CpG islands

主题词细胞分化(Cell Differentiation);细胞谱系(Cell Lineage);染色质(Chromatin);CpG岛(CpG Islands);DNA甲基化(DNA Methylation);胚胎干细胞(Embryonic Stem Cells);增强子元件, 遗传学(Enhancer Elements, Genetic);后成说, 遗传(Epigenesis, Genetic);基因表达调控, 发育期(Gene Expression Regulation, Developmental);组蛋白类(Histones);人类(Humans);启动区, 遗传(Promoter Regions, Genetic)

DOI 10.1073/pnas.1613300114

PMID 28223506

发布时间 2018-11-13

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Proceedings of the National Academy of Sciences of the United States of America

Proceedings of the National Academy of Sciences of the United States of America

2017年114卷10期

E1885-E1894页

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Proceedings of the National Academy of Sciences of the United States of America

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Proceedings of the National Academy of Sciences of the United States of America

2017年114卷10期

E1885-E1894页

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