Hyperactivation of Nrf2 in early tubular development induces nephrogenic diabetes insipidus.

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第一作者： Takafumi,Suzuki

第一单位： Department of Medical Biochemistry, Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan.

作者： Takafumi,Suzuki ^[1] ; Shiori,Seki ^[1] ; Keiichiro,Hiramoto ^[1] ; Eriko,Naganuma ^[1] ; Eri H,Kobayashi ^[1] ; Ayaka,Yamaoka ^[1] ; Liam,Baird ^[1] ; Nobuyuki,Takahashi ^[2] ; Hiroshi,Sato ^[2] ; Masayuki,Yamamoto ^[3]

作者单位： Department of Medical Biochemistry, Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan. ^[1] Department of Clinical Pharmacology and Therapeutics, Tohoku University Graduate School of Pharmaceutical Sciences Sendai, 980-8578, Japan. ^[2] Department of Medical Biochemistry, Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan.;Tohoku Medical-Megabank Organization, 2-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan. ^[3]

主题词动物(Animals);水通道蛋白质2(Aquaporin 2);细胞分化(Cell Differentiation);尿崩症, 肾性(Diabetes Insipidus, Nephrogenic);疾病模型, 动物(Disease Models, Animal);女(雌)性(Female);人类(Humans);肾盂积水(Hydronephrosis);肾小管(Kidney Tubules);男(雄)性(Male);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 基因敲除(Mice, Knockout);NF-E2相关因子2(NF-E2-Related Factor 2);氧化性应激(Oxidative Stress);多尿(Polyuria)

DOI 10.1038/ncomms14577

PMID 28233855

发布时间 2022-03-30

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Nature communications

2017年8卷

14577页

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Hyperactivation of Nrf2 in early tubular development induces nephrogenic diabetes insipidus.

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Hyperactivation of Nrf2 in early tubular development induces nephrogenic diabetes insipidus.

Nature communications

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Nature communications

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