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Epigenome-wide cross-tissue predictive modeling and comparison of cord blood and placental methylation in a birth cohort.

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第一作者： Margherita M,De Carli

第一单位： Department of Environmental Medicine & Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

作者： Margherita M,De Carli ^[1] ; Andrea A,Baccarelli ^[2] ; Letizia,Trevisi ^[3] ; Ivan,Pantic ^[4] ; Kasey Jm,Brennan ^[2] ; Michele R,Hacker ^[5] ; Holly,Loudon ^[6] ; Kelly J,Brunst ^[7] ; Robert O,Wright ^[8] ; Rosalind J,Wright ^[9] ; Allan C,Just ^[8]

作者单位： Department of Environmental Medicine & Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA. ^[1] Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY, USA. ^[2] Department of Environmental Health, Harvard TH Chan School of Public Health, Boston, MA, USA. ^[3] Department of Environmental Health, Harvard TH Chan School of Public Health, Boston, MA, USA.;Department of Developmental Neurobiology, National Institute of Perinatology, Mexico City, Mexico. ^[4] Department of Epidemiology, Harvard TH Chan School of Public Health, Boston, MA, USA.;Department of Obstetrics & Gynecology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA. ^[5] Department of Obstetrics & Gynecology, Icahn School of Medicine at Mount Sinai, New York, NY, USA. ^[6] Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, NY, USA. ^[7] Department of Environmental Medicine & Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA.;Mindich Child Health & Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA. ^[8] Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, NY, USA.;Mindich Child Health & Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA. ^[9]

关键词 450k arrays DNA methylation cord blood epigenetics methylation prediction placenta support vector machine