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Discovery of Potent Human Glutaminyl Cyclase Inhibitors as Anti-Alzheimer's Agents Based on Rational Design.

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第一作者： Van-Hai,Hoang

第一单位： Laboratory of Medicinal Chemistry, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University , Seoul 08826, Republic of Korea.

作者： Van-Hai,Hoang ^[1] ; Phuong-Thao,Tran ^[2] ; Minghua,Cui ^[3] ; Van T H,Ngo ^[1] ; Jihyae,Ann ^[1] ; Jongmi,Park ^[3] ; Jiyoun,Lee ^[4] ; Kwanghyun,Choi ^[5] ; Hanyang,Cho ^[5] ; Hee,Kim ^[5] ; Hee-Jin,Ha ^[5] ; Hyun-Seok,Hong ^[5] ; Sun,Choi ^[3] ; Young-Ho,Kim ^[5] ; Jeewoo,Lee ^[1]

作者单位： Laboratory of Medicinal Chemistry, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University , Seoul 08826, Republic of Korea. ^[1] Laboratory of Medicinal Chemistry, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University , Seoul 08826, Republic of Korea.;Department of Pharmaceutical Chemistry, Hanoi University of Pharmacy , Hanoi, Vietnam. ^[2] National Leading Research Laboratory of Molecular Modeling & Drug Design, College of Pharmacy and Graduate School of Pharmaceutical Sciences, Ewha Womans University , Seoul 03760, Republic of Korea. ^[3] Department of Global Medical Science, Sungshin University , Seoul 01133, Republic of Korea. ^[4] Medifron DBT , Sandanro 349, Danwon-Gu, Ansan-City, Gyeonggi-Do 15426, Republic of Korea. ^[5]