换一批Long-term treatment of clarithromycin at a low concentration improves hydrogen peroxide-induced oxidant/antioxidant imbalance in human small airway epithelial cells by increasing Nrf2 mRNA expression.
第一作者：
Kuninori,Iwayama
第一单位：
Department of Pharmacology & Therapeutics, Hokkaido Pharmaceutical University School of Pharmacy, 7-15-4-1 Maeda, Teine, Sapporo, Hokkaido, 006-8590, Japan.;Department of Hospital Pharmacy & Pharmacology, Asahikawa Medical University, Asahikawa, 078-8510, Japan.
作者：
医学主题词
抗氧化剂(Antioxidants);细胞存活(Cell Survival);细胞, 培养的(Cells, Cultured);克拉霉素(Clarithromycin);剂量效应关系, 药物(Dose-Response Relationship, Drug);上皮细胞(Epithelial Cells);基因表达(Gene Expression);人类(Humans);过氧化氢(Hydrogen Peroxide);白细胞介素8(Interleukin-8);NF-E2相关因子2(NF-E2-Related Factor 2);氧化剂(Oxidants);RNA, 信使(RNA, Messenger);呼吸道黏膜(Respiratory Mucosa);时间因素(Time Factors);治疗结果(Treatment Outcome)
DOI
10.1186/s40360-017-0119-8
PMID
28235416
发布时间
2022-03-21
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