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首页> Neuroscience> Resveratrol protects against spinal cord injury by activating autophagy and inhibiting apoptosis mediated by the SIRT1/AMPK signaling pathway.

Resveratrol protects against spinal cord injury by activating autophagy and inhibiting apoptosis mediated by the SIRT1/AMPK signaling pathway.

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作者： Haosen,Zhao ^[1] ; Shurui,Chen ^[2] ; Kai,Gao ^[3] ; Zipeng,Zhou ^[4] ; Chen,Wang ^[4] ; Zhaoliang,Shen ^[5] ; Yue,Guo ^[4] ; Zhuo,Li ^[5] ; Zhanghui,Wan ^[4] ; Chang,Liu ^[6] ; Xifan,Mei ^[7]

作者单位： Department of Orthopedic, First Affiliated Hospital of Jinzhou Medical University, Jinzhou City, PR China. Electronic address: 275551919@qq.com. ^[1] Department of Orthopedic, First Affiliated Hospital of Jinzhou Medical University, Jinzhou City, PR China. Electronic address: 272146792@qq.com. ^[2] Department of Orthopedics, Jining No. 1 People's Hospital, Jining City, PR China. ^[3] Department of Orthopedic, First Affiliated Hospital of Jinzhou Medical University, Jinzhou City, PR China. ^[4] Department of Orthopedics, Second Hospital of Jinzhou, Jinzhou, PR China. ^[5] Department of Endocrinology, First Affiliated Hospital of Jinzhou Medical University, Jinzhou City, PR China. Electronic address: liuchang1971mei@163.com. ^[6] Department of Orthopedic, First Affiliated Hospital of Jinzhou Medical University, Jinzhou City, PR China. Electronic address: meixifan1971@163.com. ^[7]

关键词 SIRT1/AMPK signaling pathway autophagy resveratrol spinal cord injury

主题词腺苷酸激酶(Adenylate Kinase);动物(Animals);细胞凋亡(Apoptosis);自噬(Autophagy);半胱氨酸天冬氨酸蛋白酶3(Caspase 3);半胱氨酸天冬氨酸蛋白酶9(Caspase 9);女(雌)性(Female);神经保护药(Neuroprotective Agents);原癌基因蛋白质c-bcl-2(Proto-Oncogene Proteins c-bcl-2);大鼠(Rats);大鼠, Sprague-Dawley(Rats, Sprague-Dawley);信号传导(Signal Transduction);抗衰老酶1(Sirtuin 1);脊髓(Spinal Cord);脊髓损伤(Spinal Cord Injuries);二苯乙烯类(Stilbenes)

DOI 10.1016/j.neuroscience.2017.02.027

PMID 28238848

发布时间 2022-03-30

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