第一单位：
Laboratory of Chromatin Biology &Epigenetics, The Rockefeller University, New York, New York 10065, USA.;Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.;Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02215, USA.
作者：
Liling,Wan [1]
;
Hong,Wen [2]
;
Yuanyuan,Li [3]
;
Jie,Lyu [4]
;
Yuanxin,Xi [4]
;
Takayuki,Hoshii [5]
;
Julia K,Joseph [6]
;
Xiaolu,Wang [7]
;
Yong-Hwee E,Loh [8]
;
Michael A,Erb [9]
;
Amanda L,Souza [9]
;
James E,Bradner [10]
;
Li,Shen [8]
;
Wei,Li [4]
;
Haitao,Li [3]
;
C David,Allis [6]
;
Scott A,Armstrong [5]
;
Xiaobing,Shi [11]
作者单位：
Laboratory of Chromatin Biology &Epigenetics, The Rockefeller University, New York, New York 10065, USA.;Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.;Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02215, USA.
[1]
Department of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.;Center for Cancer Epigenetics, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.
[2]
Beijing Advanced Innovation Center for Structural Biology, MOE Key Laboratory of Protein Sciences, Department of Basic Medical Sciences, School of Medicine, Tsinghua University, Beijing 100084, China.;Tsinghua-Peking Joint Center for Life Sciences, Tsinghua University, Beijing 100084, China.
[3]
Dan L. Duncan Cancer Center, Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030, USA.
[4]
Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.;Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02215, USA.
[5]
Laboratory of Chromatin Biology &Epigenetics, The Rockefeller University, New York, New York 10065, USA.
[6]
Department of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.
[7]
Fishberg Department of Neuroscience and Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.
[8]
Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts 0221, USA.
[9]
Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts 0221, USA.;Department of Medicine, Harvard Medical School, Boston, Massachusetts 02115, USA.
[10]
Department of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.;Center for Cancer Epigenetics, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.;Genes and Development and Epigenetics &Molecular Carcinogenesis Graduate Programs, The University of Texas Graduate School of Biomedical Sciences, Houston, Texas 77030, USA.
[11]
医学主题词
乙酰化作用(Acetylation);动物(Animals);细胞系, 肿瘤(Cell Line, Tumor);后成说, 遗传(Epigenesis, Genetic);女(雌)性(Female);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);组蛋白类(Histones);人类(Humans);白血病, 髓样, 急性(Leukemia, Myeloid, Acute);赖氨酸(Lysine);小鼠(Mice);癌基因(Oncogenes);启动区, 遗传(Promoter Regions, Genetic);蛋白质结合(Protein Binding);RNA聚合酶Ⅱ(RNA Polymerase II);转录, 遗传(Transcription, Genetic);转录延伸因子类(Transcriptional Elongation Factors)
DOI
10.1038/nature21687
PMID
28241141
发布时间
2019-04-16
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