The molecular mechanisms of signaling by cooperative assembly formation in innate immunity pathways.

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作者： Parimala R,Vajjhala ^[1] ; Thomas,Ve ^[2] ; Adam,Bentham ^[3] ; Katryn J,Stacey ^[1] ; Bostjan,Kobe ^[4]

作者单位： School of Chemistry and Molecular Biosciences, Institute for Molecular Bioscience and Australian Infectious Diseases Research Centre, University of Queensland, Brisbane, QLD 4072, Australia. ^[1] School of Chemistry and Molecular Biosciences, Institute for Molecular Bioscience and Australian Infectious Diseases Research Centre, University of Queensland, Brisbane, QLD 4072, Australia; Institute for Glycomics, Griffith University, Southport, QLD 4222, Australia. ^[2] School of Chemistry and Molecular Biosciences, Institute for Molecular Bioscience and Australian Infectious Diseases Research Centre, University of Queensland, Brisbane, QLD 4072, Australia; School of Biological Sciences, Flinders University, Adelaide, SA 5001, Australia. ^[3] School of Chemistry and Molecular Biosciences, Institute for Molecular Bioscience and Australian Infectious Diseases Research Centre, University of Queensland, Brisbane, QLD 4072, Australia. Electronic address: b.kobe@uq.edu.au. ^[4]

关键词 Higher-order assembly signaling Inflammasome Leucine-rich repeat-containing/nucleotide and oligomerization domain-like receptor (NLR)Nucleotide binding and oligomerization domain RIG-1-like receptor (RLR)Signaling by co-operative assembly formation (SCAF)Toll-like receptor (TLR)