Omega-3 polyunsaturated fatty acids suppress the inflammatory responses of lipopolysaccharide-stimulated mouse microglia by activating SIRT1 pathways.

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作者： Takayuki,Inoue ^[1] ; Masashi,Tanaka ^[2] ; Shinya,Masuda ^[1] ; Ryuji,Ohue-Kitano ^[1] ; Hajime,Yamakage ^[1] ; Kazuya,Muranaka ^[1] ; Hiromichi,Wada ^[3] ; Toru,Kusakabe ^[1] ; Akira,Shimatsu ^[4] ; Koji,Hasegawa ^[3] ; Noriko,Satoh-Asahara ^[1]

作者单位： Department of Endocrinology, Metabolism, and Hypertension, Clinical Research Institute, National Hospital Organization Kyoto Medical Center, 1-1 Fukakusa Mukaihata-cho, Fushimi-ku, Kyoto 612-8555, Japan. ^[1] Department of Endocrinology, Metabolism, and Hypertension, Clinical Research Institute, National Hospital Organization Kyoto Medical Center, 1-1 Fukakusa Mukaihata-cho, Fushimi-ku, Kyoto 612-8555, Japan. Electronic address: masashi.7.tanaka@gmail.com. ^[2] Division of Translational Research, Clinical Research Institute, National Hospital Organization Kyoto Medical Center, 1-1 Fukakusa Mukaihata-cho, Fushimi-ku, Kyoto 612-8555, Japan. ^[3] Clinical Research Institute, National Hospital Organization Kyoto Medical Center, 1-1 Fukakusa Mukaihata-cho, Fushimi-ku, Kyoto 612-8555, Japan. ^[4]

关键词 Autophagy Inflammation Microglia NF-κB SIRT1 ω-3 PUFAs

主题词动物(Animals);细胞因子类(Cytokines);二十二碳六烯酸类(Docosahexaenoic Acids);二十碳五烯酸(Eicosapentaenoic Acid);脂肪酸类, ω3(Fatty Acids, Omega-3);鱼油(Fish Oils);炎症(Inflammation);脂多糖类(Lipopolysaccharides);小鼠(Mice);小神经胶质细胞(Microglia);烟酰胺磷酸核糖基转移酶(Nicotinamide Phosphoribosyltransferase);危险因素(Risk Factors);信号传导(Signal Transduction);抗衰老酶1(Sirtuin 1);肿瘤坏死因子α(Tumor Necrosis Factor-alpha)

DOI 10.1016/j.bbalip.2017.02.010

PMID 28254441

发布时间 2018-09-19

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Biochimica et biophysica acta. Molecular and cell biology of lipids

2017年1862卷5期

552-560页

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Omega-3 polyunsaturated fatty acids suppress the inflammatory responses of lipopolysaccharide-stimulated mouse microglia by activating SIRT1 pathways.

Biochimica et biophysica acta. Molecular and cell biology of lipids

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Biochimica et biophysica acta. Molecular and cell biology of lipids

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Omega-3 polyunsaturated fatty acids suppress the inflammatory responses of lipopolysaccharide-stimulated mouse microglia by activating SIRT1 pathways.

Biochimica et biophysica acta. Molecular and cell biology of lipids

相似文献

Biochimica et biophysica acta. Molecular and cell biology of lipids

相关期刊

检索历史清除