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Green synthesis, inhibition studies of yeast α-glucosidase and molecular docking of pyrazolylpyridazine amines.

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第一作者： Faryal,Chaudhry

第一单位： Institute of Chemistry, University of the Punjab, Lahore 54590, Pakistan; Department of Chemistry, Kinnaird College for Women, Lahore 54000, Pakistan. Electronic address: frylchaudhry@yahoo.com.

作者： Faryal,Chaudhry ^[1] ; Abdul Qayuum,Ather ^[2] ; Mohammad Javaid,Akhtar ^[3] ; Ayesha,Shaukat ^[4] ; Mohammad,Ashraf ^[5] ; Mariya,Al-Rashida ^[6] ; Munawar Ali,Munawar ^[7] ; Misbahul Ain,Khan ^[8]

作者单位： Institute of Chemistry, University of the Punjab, Lahore 54590, Pakistan; Department of Chemistry, Kinnaird College for Women, Lahore 54000, Pakistan. Electronic address: frylchaudhry@yahoo.com. ^[1] Applied Chemistry Research Center, PCSIR Laboratories Complex, Lahore, Pakistan. ^[2] Department of Chemistry, Stony Brook University, Long Island, NY 11794-3400, USA. ^[3] Department of Biochemistry and Biotechnology, The Islamia University of Bahawalpur, Bahawalpur 63100, Pakistan. ^[4] Department of Chemistry, The Islamia University of Bahawalpur, Bahawalpur 63100, Pakistan. ^[5] Department of Chemistry, Forman Christian College (A Chartered University), Ferozepur Road, Lahore 54600, Pakistan. ^[6] Institute of Chemistry, University of the Punjab, Lahore 54590, Pakistan. ^[7] Institute of Chemistry, University of the Punjab, Lahore 54590, Pakistan; Department of Chemistry, The Islamia University of Bahawalpur, Bahawalpur 63100, Pakistan. ^[8]

关键词 Docking Green chemistry Nucleophilic substitution Pyrazolylpyridazine amines α-Glucosidase inhibitors

医学主题词胺化作用(Amination);绿色化学技术(Green Chemistry Technology);哒嗪类(Pyridazines);酿酒酵母菌(Saccharomyces cerevisiae);构效关系(Structure-Activity Relationship);α葡糖苷酶类(alpha-Glucosidases)

DOI 10.1016/j.bioorg.2017.02.003

PMID 28259376

发布时间 2020-12-09

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