Reconstruction of the metabolic network of Pseudomonas aeruginosa to interrogate virulence factor synthesis.

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作者： Jennifer A,Bartell ^[1] ; Anna S,Blazier ^[2] ; Phillip,Yen ^[2] ; Juliane C,Thøgersen ^[2] ; Lars,Jelsbak ^[3] ; Joanna B,Goldberg ^[3] ; Jason A,Papin ^[4]

作者单位： The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, 2970 Hørsholm, Denmark. ^[1] Biomedical Engineering, University of Virginia, Charlottesville, Virginia 22908, USA. ^[2] Department of Biotechnology and Biomedicine, Technical University of Denmark, 2800 Kgs. Lyngby, Denmark. ^[3] Department of Pediatrics, Division of Pulmonology, Allergy/Immunology, Cystic Fibrosis and Sleep, Children's Healthcare of Atlanta, Atlanta, Georgia 30322, USA. ^[4] Emory+Children's Center for Cystic Fibrosis Research, Emory University and Children's Healthcare of Atlanta, Atlanta, Georgia 30322, USA. ^[5]

主题词生物量(Biomass);培养基(Culture Media);基因, 细菌(Genes, Bacterial);基因, 必要(Genes, Essential);代谢网络和途径(Metabolic Networks and Pathways);模型, 生物学(Models, Biological);突变(Mutation);寡肽类(Oligopeptides);铜绿假单胞菌(Pseudomonas aeruginosa);结果可重复性(Reproducibility of Results);小分子化合物库(Small Molecule Libraries);毒力(Virulence);毒力因子类(Virulence Factors)

DOI 10.1038/ncomms14631

PMID 28266498

发布时间 2024-05-24

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Nature communications

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Reconstruction of the metabolic network of Pseudomonas aeruginosa to interrogate virulence factor synthesis.

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Reconstruction of the metabolic network of Pseudomonas aeruginosa to interrogate virulence factor synthesis.

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