Identification of novel TACE inhibitors compatible with topical application.

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作者： Gilles,Ouvry ^[1] ; Yaël,Berton ^[2] ; Yushma,Bhurruth-Alcor ^[2] ; Laetitia,Bonnary ^[2] ; Claire,Bouix-Peter ^[2] ; Karine,Bouquet ^[2] ; Marilyne,Bourotte ^[3] ; Sandrine,Chambon ^[2] ; Catherine,Comino ^[2] ; Benoît,Deprez ^[3] ; Denis,Duvert ^[2] ; Gwenaëlle,Duvert ^[2] ; Feriel,Hacini-Rachinel ^[2] ; Craig S,Harris ^[2] ; Anne-Pascale,Luzy ^[2] ; Arnaud,Mathieu ^[3] ; Corinne,Millois ^[2] ; Jonathan,Pascau ^[2] ; Artur,Pinto ^[3] ; Gaëlle,Polge ^[2] ; Arnaud,Reitz ^[2] ; Kevin,Reversé ^[2] ; Carine,Rosignoli ^[2] ; Nathalie,Taquet ^[2] ; Laurent F,Hennequin ^[2]

作者单位： Nestlé Skin Health R&D, Les Templiers 2400 Route des Colles, 06410 Biot, France. Electronic address: gilles.ouvry@galderma.com. ^[1] Nestlé Skin Health R&D, Les Templiers 2400 Route des Colles, 06410 Biot, France. ^[2] Univ. Lille, Inserm, Institut Pasteur de Lille, U1177 - Drugs and Molecules for Living Systems, F-59000 Lille, France. ^[3]

关键词 Enzyme-cell drop-off Hydroxamic acids Psoriasis TACE Topical application

主题词投药, 局部(Administration, Topical);酶抑制剂(Enzyme Inhibitors);人类(Humans);羟肟酸类(Hydroxamic Acids);银屑病(Psoriasis)

DOI 10.1016/j.bmcl.2017.02.035

PMID 28274635

发布时间 2017-11-24

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