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Chroman-4-One Derivatives Targeting Pteridine Reductase 1 and Showing Anti-Parasitic Activity.

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作者单位: Department of Biotechnology, Chemistry and Pharmacy, University of Siena, 53100 Siena, Italy. dipisa2@unisi.it. [1] Department of Biotechnology, Chemistry and Pharmacy, University of Siena, 53100 Siena, Italy. landi31@unisi.it. [2] Department of Biotechnology, Chemistry and Pharmacy, University of Siena, 53100 Siena, Italy. delloiacono3@unisi.it. [3] Department of Biotechnology, Chemistry and Pharmacy, University of Siena, 53100 Siena, Italy. pozzi4@unisi.it. [4] Department of Life Sciences, University of Modena and Reggio Emilia, Via Campi 103, 41125 Modena, Italy. chiara.borsari@unimore.it. [5] Department of Life Sciences, University of Modena and Reggio Emilia, Via Campi 103, 41125 Modena, Italy. stefania.ferrari@unimore.it. [6] Department of Life Sciences, University of Modena and Reggio Emilia, Via Campi 103, 41125 Modena, Italy. matteo.santucci@unimore.it. [7] Institute for Molecular and Cell Biology, 4150-180 Porto, Portugal and Instituto de Investigação e Inovação em Saúde, Universidade do Porto and Institute for Molecular and Cell Biology, 4150-180 Porto, Portugal. santarem@ibmc.up.pt. [8] Institute for Molecular and Cell Biology, 4150-180 Porto, Portugal and Instituto de Investigação e Inovação em Saúde, Universidade do Porto and Institute for Molecular and Cell Biology, 4150-180 Porto, Portugal. cordeiro@ibmc.up.pt. [9] Laboratório Nacional de Biociências (LNBio), Centro Nacional de Pesquisa em Energia e Materiais (CNPEM), Campinas SP13083-100, Brazil. carolinaborsoi@gmail.com. [10] Laboratório Nacional de Biociências (LNBio), Centro Nacional de Pesquisa em Energia e Materiais (CNPEM), Campinas SP13083-100, Brazil. laura.alcantara@lnbio.cnpem.br. [11] Laboratório Nacional de Biociências (LNBio), Centro Nacional de Pesquisa em Energia e Materiais (CNPEM), Campinas SP13083-100, Brazil. fontana_vanessa@yahoo.com.br. [12] Laboratório Nacional de Biociências (LNBio), Centro Nacional de Pesquisa em Energia e Materiais (CNPEM), Campinas SP13083-100, Brazil. lucio.freitas@butantan.gov.br. [13] GARDE, Instituto Butantan, São Paulo SP05503-900, Brazil. lucio.freitas@butantan.gov.br. [14] Fraunhofer Institute for Molecular Biology and Applied Ecology Screening Port, D-22525 Hamburg, Germany. Sheraz.Gul@ime.fraunhofer.de. [15] Fraunhofer Institute for Molecular Biology and Applied Ecology Screening Port, D-22525 Hamburg, Germany. Maria.Kuzikov@ime.fraunhofer.de. [16] Fraunhofer Institute for Molecular Biology and Applied Ecology Screening Port, D-22525 Hamburg, Germany. Birte.Behrens@ime.fraunhofer.de. [17] Molecular and Cellular Modeling Group, Heidelberg Institute for Theoretical Studies, 69118 Heidelberg, Germany. ina.poehner@h-its.org. [18] Molecular and Cellular Modeling Group, Heidelberg Institute for Theoretical Studies, 69118 Heidelberg, Germany. rebecca.wade@h-its.org. [19] Center for Molecular Biology (ZMBH), DKFZ-ZMBH Alliance, Heidelberg University, 69120 Heidelberg, Germany. rebecca.wade@h-its.org. [20] Interdisciplinary Center for Scientific Computing (IWR), Heidelberg University, 69120 Heidelberg, Germany. rebecca.wade@h-its.org. [21] Department of Life Sciences, University of Modena and Reggio Emilia, Via Campi 103, 41125 Modena, Italy. mariapaola.costi@unimore.it. [22] Department of Biotechnology, Chemistry and Pharmacy, University of Siena, 53100 Siena, Italy. stefano.mangani@unisi.it. [23] Magnetic Resonance Center CERM, University of Florence, 50019 Sesto Fiorentino (FI), Italy. stefano.mangani@unisi.it. [24]
DOI 10.3390/molecules22030426
PMID 28282886
发布时间 2018-12-07
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Molecules (Basel, Switzerland)

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