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Novel poly-uridine insertion in the 3'UTR and E2 amino acid substitutions in a low virulent classical swine fever virus.

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第一作者： Liani,Coronado

第一单位： Centro Nacional de Sanidad Agropecuaria (CENSA), La Habana, Cuba; IRTA, Centre de Recerca en Sanitat Animal (CReSA, IRTA-UAB), Campus de la Universitat Autònoma de Barcelona, 08193, Bellaterra, Spain.

作者： Liani,Coronado ^[1] ; Matthias,Liniger ^[2] ; Sara,Muñoz-González ^[3] ; Alexander,Postel ^[4] ; Lester Josue,Pérez ^[5] ; Marta,Pérez-Simó ^[3] ; Carmen Laura,Perera ^[5] ; Maria Teresa,Frías-Lepoureau ^[5] ; Rosa,Rosell ^[6] ; Adam,Grundhoff ^[7] ; Daniela,Indenbirken ^[7] ; Malik,Alawi ^[8] ; Nicole,Fischer ^[9] ; Paul,Becher ^[4] ; Nicolas,Ruggli ^[2] ; Llilianne,Ganges ^[10]

作者单位： Centro Nacional de Sanidad Agropecuaria (CENSA), La Habana, Cuba; IRTA, Centre de Recerca en Sanitat Animal (CReSA, IRTA-UAB), Campus de la Universitat Autònoma de Barcelona, 08193, Bellaterra, Spain. ^[1] Institute of Virology and Immunology IVI, Mittelhäusern, Switzerland. ^[2] IRTA, Centre de Recerca en Sanitat Animal (CReSA, IRTA-UAB), Campus de la Universitat Autònoma de Barcelona, 08193, Bellaterra, Spain. ^[3] EU and OIE Reference Laboratory for Classical Swine Fever, Institute of Virology, Department of Infectious Diseases, University of Veterinary Medicine, Hannover, Germany. ^[4] Centro Nacional de Sanidad Agropecuaria (CENSA), La Habana, Cuba. ^[5] IRTA, Centre de Recerca en Sanitat Animal (CReSA, IRTA-UAB), Campus de la Universitat Autònoma de Barcelona, 08193, Bellaterra, Spain; Departamentd'Agricultura, Ramaderia, Pesca, Alimentació i Medi Natural, (DAAM), Generalitat de Catalunya, Spain. ^[6] Heinrich Pette Institute, Leibniz Institute for Experimental Virology, Research Group Virus Genomics, Hamburg, Germany. ^[7] Heinrich Pette Institute, Leibniz Institute for Experimental Virology, Research Group Virus Genomics, Hamburg, Germany; Bioinformatics Service Facility, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. ^[8] Institute for Medical Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. ^[9] IRTA, Centre de Recerca en Sanitat Animal (CReSA, IRTA-UAB), Campus de la Universitat Autònoma de Barcelona, 08193, Bellaterra, Spain. Electronic address: llilianne.ganges@irta.cat. ^[10]

关键词 Amino acid differences Antigenic differences B/C domain CSFV E2 glycoprotein Immunogenicity Pigs Poly-U insertion Rabbits Secondary structure