MR image-guided delivery of cisplatin-loaded brain-penetrating nanoparticles to invasive glioma with focused ultrasound.

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第一作者： Kelsie F,Timbie

第一单位： Department of Biomedical Engineering, University of Virginia, 415 Lane Road Building MR5, Charlottesville, VA 22908, United States.

作者： Kelsie F,Timbie ^[1] ; Umara,Afzal ^[2] ; Abhijit,Date ^[3] ; Clark,Zhang ^[3] ; Ji,Song ^[1] ; G,Wilson Miller ^[4] ; Jung Soo,Suk ^[3] ; Justin,Hanes ^[3] ; Richard J,Price ^[5]

作者单位： Department of Biomedical Engineering, University of Virginia, 415 Lane Road Building MR5, Charlottesville, VA 22908, United States. ^[1] Department of Ophthalmology, The Johns Hopkins University School of Medicine, 600 N. Wolfe Street, Baltimore, MD 21287, United States; Center for Nanomedicine, The Johns Hopkins University School of Medicine, 600 N. Wolfe Street, Baltimore, MD 21287, United States; Department of Biochemistry, PMAS-Arid Agriculture University, Shamsabad, Muree Road, Rawalpindi, Pakistan. ^[2] Department of Ophthalmology, The Johns Hopkins University School of Medicine, 600 N. Wolfe Street, Baltimore, MD 21287, United States; Center for Nanomedicine, The Johns Hopkins University School of Medicine, 600 N. Wolfe Street, Baltimore, MD 21287, United States. ^[3] Department of Radiology and Medical Imaging, University of Virginia, 480 Ray C Hunt Drive, Charlottesville, VA 22908, United States. ^[4] Department of Biomedical Engineering, University of Virginia, 415 Lane Road Building MR5, Charlottesville, VA 22908, United States. Electronic address: rprice@virginia.edu. ^[5]

关键词 Blood-brain barrier Blood-tumor barrier Cisplatin Focused ultrasound Glioma Nanoparticle