TIR/BB-loop mimetic AS-1 attenuates cardiac ischemia/reperfusion injury via a caveolae and caveolin-3-dependent mechanism.

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作者： Yuanping,Hu ^[1] ; Meiling,Zhang ^[2] ; Xin,Shen ^[3] ; Guoliang,Dai ^[1] ; Danyang,Ren ^[1] ; Linli,Que ^[4] ; Tuanzhu,Ha ^[1] ; Chuanfu,Li ^[1] ; Yong,Xu ^[5] ; Wenzheng,Ju ^[5] ; Yuehua,Li ^[1]

作者单位： Key Laboratory of Cardiovascular Disease and Molecular Intervention, Department of Pathophysiology, Nanjing Medical University, 818 Tianyuan Dong Road, Nanjing 211166, Jiangsu, China. ^[1] Department of Pharmacy, The Binhu Hospital of Hefei, Hefei, Anhui, China. ^[2] Department of Pharmacy, The Binhu Hospital of Hefei, Hefei, Anhui, China; The First People Hospital of Hefei, Hefei, 230001, Anhui, China. ^[3] Affiliated Hospital of Nanjing University of Traditional Chinese Medicine, 155 Hanzhong Road, Nanjing, 210029, China. ^[4] Department of Surgery, East Tennessee State University, Campus Box 70575, Johnson City, TN 37614-0575, USA. ^[5]

主题词动物(Animals);细胞凋亡(Apoptosis);强心药(Cardiotonic Agents);细胞质膜微囊(Caveolae);窖蛋白3(Caveolin 3);细胞系(Cell Line);超声心动描记术(Echocardiography);基因表达(Gene Expression);男(雄)性(Male);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);心肌再灌注损伤(Myocardial Reperfusion Injury);心肌(Myocardium);肌细胞, 心脏(Myocytes, Cardiac);多肽模拟物(Peptidomimetics);RNA, 小分子干扰(RNA, Small Interfering);大鼠(Rats);大鼠, Wistar(Rats, Wistar)

DOI 10.1038/srep44638

PMID 28291255

发布时间 2018-11-13

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TIR/BB-loop mimetic AS-1 attenuates cardiac ischemia/reperfusion injury via a caveolae and caveolin-3-dependent mechanism.

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TIR/BB-loop mimetic AS-1 attenuates cardiac ischemia/reperfusion injury via a caveolae and caveolin-3-dependent mechanism.

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