换一批Alkaline ceramidase 2 is a novel direct target of p53 and induces autophagy and apoptosis through ROS generation.
第一作者：
Yitao,Wang
第一单位：
Department of Biochemistry and Molecular Biology, Chongqing Medical University, Chongqing 400016, China.;Molecular Medicine and Cancer Research Center, Chongqing Medical University, Chongqing 400016, China.
作者：
医学主题词
碱性神经酰胺酶(Alkaline Ceramidase);细胞凋亡(Apoptosis);自噬(Autophagy);DNA损伤(DNA Damage);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);人类(Humans);肺肿瘤(Lung Neoplasms);蛋白质结合(Protein Binding);活性氧(Reactive Oxygen Species);肿瘤抑制蛋白质p53(Tumor Suppressor Protein p53)
DOI
10.1038/srep44573
PMID
28294157
发布时间
2025-01-05
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