Discovery of three toxin peptides with Kv1.3 channel and IL-2 cytokine-inhibiting activities from Non-Buthidae scorpions, Chaerilus tricostatus and Chaerilus tryznai.

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第一作者： Li,Ding

第一单位： Department of Biochemistry and Molecular Biology, Institute of Basic Medical Sciences, College of Basic Medicine, Hubei University of Medicine, Hubei, China; Department of Clinical Laboratory, Dongfeng Hospital, Hubei University of Medicine, Hubei, China.

作者： Li,Ding ^[1] ; Jing,Chen ^[2] ; Jinbo,Hao ^[3] ; Jiahui,Zhang ^[4] ; Xuejun,Huang ^[4] ; Fangfang,Hu ^[4] ; Zheng,Wu ^[4] ; Yaru,Liu ^[4] ; Wenxin,Li ^[2] ; Zhijian,Cao ^[2] ; Yingliang,Wu ^[2] ; Jian,Li ^[4] ; Shan,Li ^[1] ; Hongyan,Liu ^[1] ; Wenlong,Wu ^[1] ; Zongyun,Chen ^[5]

作者单位： Department of Biochemistry and Molecular Biology, Institute of Basic Medical Sciences, College of Basic Medicine, Hubei University of Medicine, Hubei, China; Department of Clinical Laboratory, Dongfeng Hospital, Hubei University of Medicine, Hubei, China. ^[1] State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Hubei, China. ^[2] Department of Clinical Laboratory, Shiyan Occupational Disease Hospital, Hubei, China. ^[3] Department of Biochemistry and Molecular Biology, Institute of Basic Medical Sciences, College of Basic Medicine, Hubei University of Medicine, Hubei, China. ^[4] Department of Biochemistry and Molecular Biology, Institute of Basic Medical Sciences, College of Basic Medicine, Hubei University of Medicine, Hubei, China. Electronic address: chenzy2005@126.com. ^[5]

关键词 Chaerilidae IL-2 Kv1.3 channel Potential immunoregulatory peptide Scorpion toxin