Epigenomic Promoter Alterations Amplify Gene Isoform and Immunogenic Diversity in Gastric Adenocarcinoma.
作者:
Aditi,Qamra [1]
;
Manjie,Xing [2]
;
Nisha,Padmanabhan [3]
;
Jeffrey Jun Ting,Kwok [4]
;
Shenli,Zhang [3]
;
Chang,Xu [5]
;
Yan Shan,Leong [3]
;
Ai Ping,Lee Lim [3]
;
Qianqao,Tang [6]
;
Wen Fong,Ooi [1]
;
Joyce,Suling Lin [7]
;
Tannistha,Nandi [1]
;
Xiaosai,Yao [1]
;
Xuewen,Ong [1]
;
Minghui,Lee [1]
;
Su Ting,Tay [3]
;
Angie Tan Lay,Keng [3]
;
Erna,Gondo Santoso [3]
;
Cedric Chuan Young,Ng [3]
;
Alvin,Ng [7]
;
Apinya,Jusakul [7]
;
Duane,Smoot [3]
;
Hassan,Ashktorab [4]
;
Sun Young,Rha [3]
;
Khay Guan,Yeoh [8]
;
Wei,Peng Yong [9]
;
Pierce K H,Chow [10]
;
Weng Hoong,Chan [11]
;
Hock Soo,Ong [12]
;
Khee Chee,Soo [13]
;
Kyoung-Mee,Kim [14]
;
Wai Keong,Wong [15]
;
Steven G,Rozen [16]
;
Bin Tean,Teh [16]
;
Dennis,Kappei [15]
;
Jeeyun,Lee [17]
;
John,Connolly [16]
;
Patrick,Tan [3]
作者单位:
Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore, Singapore.
[1]
Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
[2]
Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore.
[3]
NUS Graduate School for Integrative Sciences and Engineering, National University of Singapore, Singapore.
[4]
Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore.
[5]
Cancer Science Institute of Singapore, National University of Singapore, Singapore.
[6]
Laboratory of Cancer Epigenome, Department of Medical Sciences, National Cancer Centre, Singapore.
[7]
Department of Internal Medicine, Meharry Medical College, Nashville, Tennessee.
[8]
Department of Medicine, Howard University, Washington, DC.
[9]
Department of Internal Medicine, Yonsei University College of Medicine, Seoul, South Korea.
[10]
Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore.
[11]
Department of Gastroenterology & Hepatology, National University Hospital, Singapore.
[12]
Department of Haematology-Oncology, National University Hospital of Singapore, Singapore.
[13]
Department of General Surgery, Singapore General Hospital, Singapore.
[14]
Division of Surgical Oncology, National Cancer Centre Singapore, Singapore.
[15]
Department of Upper Gastrointestinal & Bariatric Surgery, Singapore General Hospital, Singapore.
[16]
Department of Pathology & Translational Genomics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
[17]
SingHealth/Duke-NUS Institute of Precision Medicine, National Heart Centre Singapore, Singapore.
[18]
Department of Medicine, Division of Hematology-Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
[19]
Institute of Biomedical Studies, Baylor University, Waco, Texas.
[20]
Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore, Singapore. gmstanp@duke-nus.edu.sg.
[21]
Cellular and Molecular Research, National Cancer Centre, Singapore.
[22]
主题词
腺癌(Adenocarcinoma);细胞系, 肿瘤(Cell Line, Tumor);表观基因组学(Epigenomics);人类(Humans);启动区, 遗传(Promoter Regions, Genetic);胃肿瘤(Stomach Neoplasms)
DOI
10.1158/2159-8290.CD-16-1022
PMID
28320776
发布时间
2018-03-06
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Cancer discovery
Cancer discovery
630-651页
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