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Activation of the intronic cryptic 5' splice site depends on its distance to the upstream cassette exon.

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第一作者： Wei,Liu

第一单位： Department of Hepatobiliary Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi Province, China.

作者： Wei,Liu ^[1] ; Xia,Li ^[1] ; Shengjie,Liao ^[2] ; Kefeng,Dou ^[3] ; Yi,Zhang ^[4]

作者单位： Department of Hepatobiliary Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi Province, China. ^[1] Center for Genome Analysis, ABLife Inc., Optics Valley International Biomedical Park, Building 9-4, East Lake High-Tech Development Zone, 388 Gaoxin 2nd Road, Wuhan, Hubei 430075, China; Laboratory for Genome Regulation and Human Heath, ABLife Inc., Optics Valley International Biomedical Park, Building 9-4, East Lake High-Tech Development Zone, 388 Gaoxin 2nd Road, Wuhan, Hubei 430075, China. ^[2] Department of Hepatobiliary Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi Province, China. Electronic address: gdwkgwx@fmmu.edu.cn. ^[3] Center for Genome Analysis, ABLife Inc., Optics Valley International Biomedical Park, Building 9-4, East Lake High-Tech Development Zone, 388 Gaoxin 2nd Road, Wuhan, Hubei 430075, China; Laboratory for Genome Regulation and Human Heath, ABLife Inc., Optics Valley International Biomedical Park, Building 9-4, East Lake High-Tech Development Zone, 388 Gaoxin 2nd Road, Wuhan, Hubei 430075, China. Electronic address: yizhang@ablife.cc. ^[4]

关键词 Alternative splicing Cryptic splice site ESE Positional effect Splice site selection