Pharmacological inhibition of adipose triglyceride lipase corrects high-fat diet-induced insulin resistance and hepatosteatosis in mice.

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作者： Martina,Schweiger ^[1] ; Matthias,Romauch ^[1] ; Renate,Schreiber ^[1] ; Gernot F,Grabner ^[1] ; Sabrina,Hütter ^[1] ; Petra,Kotzbeck ^[1] ; Pia,Benedikt ^[1] ; Thomas O,Eichmann ^[1] ; Sohsuke,Yamada ^[1] ; Oskar,Knittelfelder ^[1] ; Clemens,Diwoky ^[1] ; Carina,Doler ^[2] ; Nicole,Mayer ^[2] ; Werner,De Cecco ^[3] ; Rolf,Breinbauer ^[2] ; Robert,Zimmermann ^[1] ; Rudolf,Zechner ^[1]

作者单位： Institute of Molecular Biosciences, University of Graz, Heinrichstrasse 31, 8010 Graz, Austria. ^[1] Institute of Organic Chemistry, Graz University of Technology, Stremayrgasse 9, 8010 Graz, Austria. ^[2] Institute of Chemistry, University of Graz, Heinrichstrasse 28, 8010 Graz, Austria. ^[3]

主题词脂肪组织, 白色(Adipose Tissue, White);动物(Animals);体重(Body Weight);脂肪肝(Fatty Liver);摄食行为(Feeding Behavior);葡萄糖(Glucose);内环境稳定(Homeostasis);人类(Humans);胰岛素抗药性(Insulin Resistance);脂肪酶(Lipase);脂解作用(Lipolysis);男(雄)性(Male);小鼠, 近交C57BL(Mice, Inbred C57BL);肥胖症(Obesity);苯脲化合物(Phenylurea Compounds)

DOI 10.1038/ncomms14859

PMID 28327588

发布时间 2022-03-11

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Nature communications

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Pharmacological inhibition of adipose triglyceride lipase corrects high-fat diet-induced insulin resistance and hepatosteatosis in mice.

Nature communications

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Pharmacological inhibition of adipose triglyceride lipase corrects high-fat diet-induced insulin resistance and hepatosteatosis in mice.

Nature communications

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Nature communications

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