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Conserved Atg8 recognition sites mediate Atg4 association with autophagosomal membranes and Atg8 deconjugation.

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第一作者： Susana,Abreu

第一单位： Department of Cell Biology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.;Department of Cell Biology, University Medical Center Utrecht, Utrecht, The Netherlands.

作者： Susana,Abreu ^[1] ; Franziska,Kriegenburg ^[1] ; Rubén,Gómez-Sánchez ^[1] ; Muriel,Mari ^[1] ; Jana,Sánchez-Wandelmer ^[1] ; Mads,Skytte Rasmussen ^[2] ; Rodrigo,Soares Guimarães ^[1] ; Bettina,Zens ^[3] ; Martina,Schuschnig ^[3] ; Ralph,Hardenberg ^[4] ; Matthias,Peter ^[5] ; Terje,Johansen ^[2] ; Claudine,Kraft ^[3] ; Sascha,Martens ^[3] ; Fulvio,Reggiori ^[6]

作者单位： Department of Cell Biology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.;Department of Cell Biology, University Medical Center Utrecht, Utrecht, The Netherlands. ^[1] Molecular Cancer Research Group, Institute of Medical Biology, University of Tromsø - The Arctic University of Norway, Tromsø, Norway. ^[2] Department of Biochemistry and Cell Biology, Max F. Perutz Laboratories (MFPL), Vienna Biocenter (VBC), University of Vienna, Vienna, Austria. ^[3] Department of Cell Biology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. ^[4] Department of Biology, Institute of Biochemistry, Swiss Federal Institute of Technology, Zurich, Switzerland. ^[5] Department of Cell Biology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands f.m.reggiori@umcg.nl.;Department of Cell Biology, University Medical Center Utrecht, Utrecht, The Netherlands. ^[6]

关键词 LC3 autophagosome autophagy deconjugation phagophore assembly site